depression Flashcards
what kind of disorder is depression
affective disorder
name 4 types of symptoms of depression
- cognitive
- behavioral
- somatic (physical)
- affective (mood)
example of somatic symptom of depression
sleep difficulties
example of affecitve symptom of depression
depressed
worthless
what is reactive depression caused by
caused by negative experience
what is endogenous depression
no apparent negative lfie event
define bipolar
periods of mania occur
what is brown et al 1993 findings
depressed patients experience higher levels fo stress
84% depressed felt stress in previous year
32% of control group
what is the CR rate for depression in mz twins
60%
what is the CR rate for depression in dz twins
15%
What does the diathesis stress model show
people who have risk factor gene = higher chance of depression when exposed to stress
how were anti depressant drugs found
LUCK
what is an example of maoi
irproniazid
what do MAO inhibitors do
increase monoamine available by inhibiting monoamine oxidase in cytoplasm
what feelings do MAOI cause
feelings of calm
name the 2 tyoes of monoamine transmitters
- catecholamines
2. indolamines
name examples of catecholamines
dopamine, adrenaline and noradrenaline
name example of idolamine
seretonin
where do NT projections and NT occur
raphe nucleus
where do noradrenaline projections occur
dorsal and ventral projections
what is monoamine oxidase
enzyme that breaks down NT for monoamine
what do MAO inhibitors do
STOP BREAKDOWN - more NT available in neuron
what is tyramine normally broken down by
Monoamine oxidase in liver
what does tyramine cause if not broken down
increase in blood pressure
