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Pharmacology > Steroids > Flashcards

Steroids Flashcards

1
Q

What is are the side effects of steroids?

A

Pneumonic = CUSHINGOID

Cataracts
Ulcers
Striae, skin thinning 
Hypertension 
Immunosuppression 
Necrosis of femoral head
Glucose elevation
Osteoporosis 
Impaired wound healing 
Depression
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2
Q

What are common steroids used?

A 
Prednisolone 
Hydrocrotisone 
Betamethasone 
Dexamethasone
Fludrocortisone
Beclomethasone diproprionate
Budesonide
Fluticasone
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3
Q

What is the mechanism of corticosteroids?

A

Prevent IL-1 + IL-6 production by macrophages
Inhibit all stages of T cell activation

Fewer immune cells = less inflammation

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4
Q

What is the route of administration of prednisolone?

A

Oral

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5
Q

What are the indications for prednisolone?

A 
Exacerbation of COPD
Severe croup 
Asthma 
ITP
Suppression of inflammation + allergy 
IBD
PMR
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6
Q

What are the routes of administration for hydrocortisone?

A

IV
Transdermal
Oral

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7
Q

What are the indications for hydrocortisone?

A 
Thyrotoxic crisis 
Acute hypersensitivity reactions
Adrenocortical insufficiency 
Severe IBD
Severe asthma
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8
Q

What are the routes of administration of betamethasone?

A

Eye drops

Skin

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9
Q

What are the indications for betamethasone?

A

Local inflammation

Severe inflammatory disorders

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10
Q

What are the routes of administration of dexamethasone?

A

Oral

Eye drops

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11
Q

What are the indications for dexamethasone?

A

Suppression of inflammatory and allergic disorders
Croup
Dexamethasone suppression test
Bacterial meningitis

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12
Q

What are the routes of administration of fludrocortisone?

A

Oral

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13
Q

What are the indications for fludrocortisone?

A

Mineralocorticoid replacement

Neuropathic postural hypotension

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14
Q

What are the routes of administration of beclometasone diproprionate?

A

Inhalation

Skin

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15
Q

What are the indications of beclometasone diproprionate?

A

Astham
Allergic/vasomotor rhinitis
Severe inflammatory skin disorders

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16
Q

What are the routes of administration of budesonide?

A

Inhalation

Intranasal

17
Q

What are the indications for budesonide?

A

Asthma
Allergic rhinitis
Nasal polyps

18
Q

What are the routes of administration of fluticasone?

A

Inhalation
Intranasal
Skin

19
Q

What are the indications for fluticasone?

A

Asthma
Allergic rhinitis
Nasal polyps
Severe inflammatory skin disorders

Pharmacology (27 decks)

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