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Pharmacology > Insulin > Flashcards

Insulin Flashcards

1
Q

What is the role of insulin?

A

Stimulates uptake of glucose into cells
Inhibits gluconeogenesis
Inhibits glycogenolysis
Promotes uptake of fats

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2
Q

What are the main insulin categories?

A 
Ultrafast acting
Rapid acting 
Short acting 
Intermediate acting 
Long acting 
Very long acting
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3
Q

How is insulin administered?

A

SC

IV

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4
Q

What is an example of an ultrafast acting insulin?

A

Aspart (FiAsp)

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5
Q

How quickly does ultrafast insulin act?

A

Within 10 mins

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6
Q

What are examples of rapid acting insulins?

A

Novorapid
Humalog
Apidra

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7
Q

What is the onset of rapid acting insulin?

A

5-15 mins

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8
Q

When does rapid acting insulin peak?

A

60 mins

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9
Q

What is the duration of action of rapid acting insulin?

A

4-6 hours

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10
Q

What are examples of short acting insulins?

A

Actrapid

Humalin S

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11
Q

What is the onset of short acting insulin?

A

30-60 mins

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12
Q

When does short acting insulin peak?

A

2-3 hrs

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13
Q

How soon before meals should short acting insulins be injected?

A

15-30 mins

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14
Q

What is the duration of action of short acting insulin?

A

8-10 hrs

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15
Q

What are examples of intermediate acting insulin?

A

Insulatard

Humulin I

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16
Q

What is the onset of intermediate insulin?

A

2-4 hours

17
Q

When does intermediate insulin peak?

A

4-8 hours

18
Q

What is the duration of action of intermediate insulin?

A

12-20hrs

19
Q

What are examples of long acting insulin?

A

Glargine
Detemir
Degludec

20
Q

What is the onset of long acting insulin?

A

2-6 hours

21
Q

What is the duration of action of long acting insulin?

A

Up to 24 hours

22
Q

What are adverse effects of insulin?

A

Hypoglycaemia
Hyperglycaemia
Lipodystrophy
Painful injections

Pharmacology (27 decks)

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