Anti-diarrhoeals Flashcards
1
Q
What is the best way to stop diarrhoea?
A
Treat the cause
2
Q
What is the class of anti-diarrhoeal used?
A
Opioid receptor agonist
3
Q
What are examples of opioid receptor agonist?
A
Loperamide
Codeine
Morphine
4
Q
What is the mechanism of loperamide
A
Specific to μ receptors
- decreases tone of longitudinal + circular smooth muscle
- reduces peristalsis
- decreases colonic mass movement
- supresses gastrocolic reflex
5
Q
What is the route of administration of loperamide?
A
Oral
6
Q
What are side effects of opioid receptor agonists?
A
Paralytic ileus
N+V
Sedation
