Steroid And Fat-Soluble Vitamins Flashcards

1
Q

Progesterone

A

From corpus luteum and placenta, chief hormone of pregnancy

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2
Q

Estradiol

A

Made by aromatase from testosterone in the ovaries

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3
Q

Testosterone

A

Made by testes, responsible for secondary sex characteristics

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4
Q

Aromatase

A

Catalyzes the reaction from testosterone to estradiol

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5
Q

Aldosterone

A

Regulate electrolyte resorption in th kidney

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6
Q

Cortisol

A

Regulates metabolism, made by the adrenal cortex

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7
Q

Fat soluble vitamins

A

A, D, E, K

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8
Q

Vitamin that can be synthesized De Novo

A

Vitamin D

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9
Q

3 forms of vitamin A

A

Trans-retinal
Retinol
Retinoic acid

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10
Q

Retinoic acid

A

Hormone important in growth and differentiation, works like a steroid receptor

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11
Q

Retinal

A

Binds to ops in to form rhodopsin, first signal in vision

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12
Q

Vitamin A deficiency

A

Night blindness

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13
Q

Vitamin D deficiency

A

Made biosynthetically or from diet, results in weak bones

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14
Q

Order of vitamin D synthesis

A

Skin (triggered by UV light), Liver, Kidney (creates most active 1,25 (OH)2D3

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15
Q

Vitamin D mechanism of action

A

Activates vitamin D dependent transcription factor that mediates calcium absorption in the gut

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16
Q

Vitamin E

A

Alpha-tocopherol is an important antioxidant that terminates free radical oxidation of unsaturated FAs

17
Q

Vitamin K

A

Mediates clotting by acting as a cofactor for Corboxylase of glutamate

18
Q

Warfarin

A

Anti coagulant that can be lethal at high levels