stereoisomerism

Question 1

what have the same order of attachment of atoms but different arrangements of atoms in space

Answer 1

stereoisomerism

Question 2

define stereoisomerism

Answer 2

have the same order of attachment of atoms but different arrangements of atoms in space

Question 3

stereoisomerism is responsible for the significant difference in

Answer 3

chemical properties

Question 4

effectiveness of … depends on stereoisomerism

Answer 4

drugs

Question 5

stereoisomerism may have the presence/ absence of

Answer 5

side effects

Question 6

which has a superimposable image

Answer 6

achiral

Question 7

which do not have a superimposable image

Answer 7

chiral

Question 8

which has a plane of symmetry

Answer 8

achiral

Question 9

which does not have a plane of symmetry

Answer 9

chiral

Question 10

what way is a quick way to tell if it’s chiral or not

Answer 10

plane of symmetry

Question 11

which is able to rotate plane-polarized light

Answer 11

chiral (optically active substance)

Question 12

which is not able to rotate plane-polarized light

Answer 12

achiral (optically inactive substance)

Question 13

carbon with 4 different groups attached to it

Answer 13

stereogenic carbon / stereogenic center

Question 14

what refers to a pair (chiral and mirror image) of molecules related as nonsuperimposable

Answer 14

enantiomers

Question 15

pairs of compounds with exactly the same connectivity but opposite three-dimensional shapes

Answer 15

enantiomers

Question 16

what refers to a plane that passes through a molecule

Answer 16

plane of symmetry/ mirror plane

Question 17

plane of symmetry is where one side of the plane is the…

Answer 17

exact reflection of the other side

Question 18

what is the ARRANGEMENT of 4 groups attached to a stereogenic center

Answer 18

configuration

Question 19

is enantiomers a configuration or opposite configuration

Answer 19

opposite configuration

Question 20

what refers to the specify of the configuration w/o having to draw the structure

Answer 20

R-S or Cahn-Inlog-Prelog System

Question 21

what is the R-S / Cahn-Ingold-Prelog System conditions

Answer 21

observe from the side opposite of the lowest priority

Question 22

how do you arrange them from highest to lowest priority

Answer 22

by looking at the atomic number

Question 23

(R):

Answer 23

clockwise

Question 24

(S):

Answer 24

counterclockwise

Question 25

in the Cahn-Ingold-Prelog System, how do u rank them

Answer 25

rank the atoms attached too stereogenic center.

Question 26

the higher the atomic number...

Answer 26

the higher the priority

Question 27

in Cahn-Ingold-Prelog System, if the first step or decision could not be reached...

Answer 27

work outward from stereogenic center

Question 28

in Cahn-Ingold-Prelog System, the double, triple bonds aromatic rings are treated as...

Answer 28

as equal no. of single bonds

Question 29

what can contain 0 or 1 or more chirality centers

Answer 29

chiral molecule

Question 30

what uses the same priority rule

Answer 30

the E-Z convention for cis-trans isomers

Question 31

(E):

Answer 31

2 higher group are on the opposite side of double bond

Question 32

(Z):

Answer 32

2 higher group are on the same side of double bond

Question 33

what is the instruments used to detect optical activity

Answer 33

polarimeter/ spectropolarimeter

Question 34

in the polarized light and optical activity, what is able to rotate the plane-polarized light

Answer 34

optically active substances (chiral)

Question 35

in the polarized light and optical activity, what is unable to rotate the plane-polarized light

Answer 35

optically inactive substances (achiral)

Question 36

in the polarized light and optical activity, which rotates through an angle a

Answer 36

optically active substances (chiral)

Question 37

2 enantiomers rotate plane-polarized light to a same...

Answer 37

to a same angle but opposite directions

Question 38

the properties of enantiomers differ only with respect to

Answer 38

chirality

Question 39

enantiomers are identical in terms of

Answer 39

BP,MP, solubility

Question 40

what is the interchange of any 2 groups that always give the enantiomers

Answer 40

stereorepresentations

Question 41

how to determine the absolute (R/S) configuration of stereoisomer

Answer 41

1. check which has the highest priority (make sure that the H is at the vertical line) 2. know if it's clockwise or anticlockwise

Question 42

what to do if the lowest priority is at the horizontal lines

Answer 42

you could rotate 3 of the 4 groups so that the lowest priority is at the vertical line

Question 43

do compound with more than 1 chirality center have or dont have mirror image

Answer 43

have mirror image

Question 44

do stereoisomeric forms have or dont have mirror image

Answer 44

dont have mirror image

Question 45

based on my understanding, what is constitutional, configurational and identical

Answer 45

constitutional - completely different configurational - geometric (cis/ trans) same mol. formula but diff attachment of atom identical - everything is the same

Question 46

An achiral compound with chiral centres

Answer 46

meso compounds

Question 47

what are meso compounds

Answer 47

An achiral compound with chiral centres

Question 48

what has an internal plane of symmetry that makes it superimposable on its mirror image and is optically inactive

Answer 48

meso compound

Question 49

what is an isomers that has the same chemical formula but non superimposable mirror image of e/o

Answer 49

enantiomers

Question 50

what is an arrangement of elements in a particular form

Answer 50

configuration

Question 51

you automatically have one enantiomers when...

Answer 51

you have one chiral center

Question 52

the enantiomers will always have different...

Answer 52

configuration

Question 53

in the cahn-ingold-prelog rules, if the lowest priority is at the front...

Answer 53

need to reverse the direction.

Question 54

both or all chiral centers has changed and no internal plane of symmetry

Answer 54

enantiomers

Question 55

differ by only one chiral centers

Answer 55

diastereomers

Question 56

identical and have an internal plane of symmetry

Answer 56

meso compounds

Question 57

in optical activity, positive or negative enantiomers if it rotates towards the right

Answer 57

positive

Question 58

in optical activity, positive or negative enantiomers if it rotates towards the left

Answer 58

negative

Question 59

if positive enantiomers, is it dextrorotary or levorotatory

Answer 59

dextrorotary

Question 60

if negative enantiomers, is it dextrorotary or levorotatory

Answer 60

levorotatory