step 3 13 Flashcards

1
Q

inflammatory myopathies are

A

PM/DM

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2
Q

polymyalgia rheumatica presentation

A

Systemic signs & symptoms

Stiffness > pain in shoulders, hip girdle, neck

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3
Q

PM management

A

systemic glucocorticoids, often with corticosteroid-sparing agents (eg, methotrexate, azathioprine)
Monitor for respiratory complications (ILD, diaphragm weakness) with PFTs if SOB
Cancer screening (can be paraneoplastic)

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4
Q

fibromyalgia presentation

A

Chronic widespread pain
Fatigue, impaired concentration
Tenderness at trigger points (eg, mid trapezius, costochondral junction)

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5
Q

back pain red flags

A

nighttime pain, age >50, unexplained weight loss, history of malignancy

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6
Q

management of back pain if red flags positive

A

ESR + plain film

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7
Q

polycythemia management

A

Check to see if on testosterone → order ABG to exclude hypoxia → if normal get epo level + hematology consult + nuclear red cell mass test for JAK2 (PV)

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8
Q

nephrolithiasis management

A

IF <5 mm, nothing (will pass spontaneously)
IF5- 10 mm – trial medical therapy (gentle hydration, pain control, alpha blockers). No admission if symptoms are controlled.
IF >10 mm, persistent pain, acute renal failure, or signs of sepsis → consult surgery

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9
Q

RSV/bronchiolities presentation

A

URI + increased work of breathing + wheezing

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10
Q

common sequela of RSV

A

recurrent wheezing

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11
Q

how to confirm brain death

A

apnea testing

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12
Q

doxazosin

A

alpha blocker used for BPH

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13
Q

NSTEMI orders

A

Dual antiplatelet therapy with aspirin and platelet P2Y12 receptor blockers (clopidogrel, prasugrel, or ticagrelor)
Nitrates
Beta blockers
Statins
Anticoagulant therapy (unfractionated heparin, low-molecular-weight heparin, bivalirudin, or fondaparinux)

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14
Q

primary treatment for invasive squamous cell skin cancer

A

surgery

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15
Q

indications for biventricular pacemaker

A

1) Left ventricular ejection fraction < 35%,
2) QRS duration of > 120 ms
3) New York Heart Association (NYHA) functional class III or IV with optimal medical therapy

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16
Q

graves disease vs. silent thyroiditis and postpartum thyroiditis on RAIU

A

thyroid hormone synthesis, from PT and silent thyroiditis, which are characterized by thyroid inflammation and release of preformed hormone. Graves disease has a high RAIU, whereas PT and silent thyroiditis have a low RAIU

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17
Q

sensitivity analysis in research

A

repeating primary analysis calculations in a study by modifying certain criteria or variable ranges to determine whether such modifications significantly affect the results initially obtained

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18
Q

Propensity scoring

A

weighs different variables (eg, severity of different comorbidities) in both the treatment and the control groups to ensure that these variables are balanced between both groups. An individual in the treatment group can be matched with an individual in the control group who has a similar propensity score. Matching can also be conducted based on similar variables (eg, age, sex) even in the absence of propensity scoring.

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19
Q

management of exercise induced functional amenorrhea

A

Increased caloric intake
Estrogen
Calcium & vitamin D

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20
Q

problem with gingko

A

increased bleeding risk

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21
Q

side effects of OCPs

A

Unscheduled bleeding is the most common side effect of the combined oral contraceptive pill and occurs due to a thin atrophic unstable endometrium that sheds erratically. Oral contraceptives do not cause weight gain or impaired fertility.

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22
Q

management of parent refusing life-saving care for child

A

If a parent refuses medically necessary care for a child in an emergency situation, treatment should proceed while simultaneously seeking a court order to continue care.

23
Q

Pregnancy-induced pruritus presentation

A

pruritus in pregnancy with no skin changes. very common.

24
Q

intrahepatic cholestasis of pregnancy presentation

A
Generalized pruritus
Hands &amp; foot involvement
No rash
↑ Bile acids
Transaminitis
25
management of intrahepatic cholestasis of pregnancy
Delivery at 37 weeks Ursodeoxycholic acid Antihistamines
26
cutoff for reduced vs preserved heart failure
LVEF ≤40
27
cognitive testing suggestive of dementia
MMSE (score <24/30 suggestive of MCI/dementia) | Montreal Cognitive Assessment (score <26/30)
28
common complication of CABG
pericarditis
29
selection bias
sample is unrepresentative of target population
30
nonresponse bias
high rate of nonresponders to survey/questionnaires alters results
31
attrition bias
high drop out rate can introduce bias if drop out people differ significantly
32
prevalence bias
exposures that happen long before disease assessment can cause study to miss diseased patients that die early or recover
33
erb duchenne palsy cause
macrosomia leading to shoulder dystocia
34
skin tag associations
obesity, insulin resistance, overt diabetes, and metabolic syndrome.
35
derm association of GI malignancy
Explosive onset of multiple itchy, seborrheic keratoses
36
IBD derm association
Pyoderma gangrenosum
37
acanthosis nigricans
Insulin resistance | Gastrointestinal malignancy
38
polyhydramnios definition
an amniotic fluid index >24 cm
39
polyhydramnios causes
maternal diabetes mellitus (osmotic diuresis, fetal polyuria, and polyhydramnios) and congenital anomalies (eg, anencephaly, duodenal atresia)
40
polyhydramnios complications
Fetal malposition Umbilical cord prolapse Preterm labor Preterm premature rupture of membranes
41
oligohydramnios complications
Meconium aspiration Preterm delivery Umbilical cord compression
42
oligohydramnios causes
``` Preeclampsia Abruptio placentae Uteroplacental insufficiency Renal anomalies NSAIDs ```
43
evidence for st johns wort
good evidence for mild to moderate depression
44
presentation of esophageal perforation
repeated episodes of vomiting + left-side pleural effusion
45
grief versus depression
Persistent sadness, pervasive anhedonia, and functional impairment
46
G6PD presentation in newborn
neonatal period on day of life 2-3 with unconjugated hyperbilirubinemia and anemia
47
point of funnel plots
publication bias
48
biggest risk factor for PID
multiple sexual partners
49
NF2
bilateral deafness (from acoustic neuromas) + hypopigmented spots (cafe-au-lait)
50
postpartum endometritis abx
clindamycin and gentamicin
51
PPV equation
PPV = True positives ÷ (True positives + False positives)
52
NPV equation
NPV = True negatives ÷ (True negatives + False negatives)
53
positive LR equation
sensitivity / (1 − specificity)
54
negative LR equation
(1 − sensitivity) / specificity