Statin Flashcards
Atorvastatin trade name
lipitor
atorvastatin drug classification
antilipidemic, statin
atoravastatin expected effect
inhibit HMG- CoA enzyme to reduce cholesterol synthesis. High doses lead to plaque regression
atoravastatin why use
hypercholesterolemia
dysbetalipoproteinemia
^ triglyceride levels
- prevention CVD by reducing heart risk in those with ^ cholesterol
atoravastatin route of admin
PO
atoravastatin dosages
10-80mg/day
atoravastatin adverse effects
liver dysfunction
pancreatitis
rhabdomyolysis
atoravastatin nursing implications
hypercholesterolemia (diet, triglyceride levels)
hepatic studies
renal studies
bowel status (constipation)
rhabdomyolysis (muscle pain, CPK)
evaluate: decrease LDL, cholesteril, CAD, triglycerides, ^ HDL
teach: bloodwork, stop smoking, diet, exercise, eye exam, photosensitivity
NOT TO TAKE IF PREGNANT OR BREASTFEEDING, NO ALCOHOL
rosuvastain trade name
crestor
rosuvastatin drug classification
statin
rosuvastatin expected effect
inhibit HMG- CoA reductase enzyme which reduces cholesterol synthesis
rosuvastatin route of admin
PO
rosuvastatin why use
- hypercholesterolemia
- CVD
- MI, stroke
- slow progression atherosclerosis
- ^ triglyceride levels
rosuvastatin dosages
MI/ stroke: 5-20mg
atherosclerosis: 20mg/day
hypercholesterolemia (family): 20mg/day max 40
hypercholesterolemia: 5-40mg, initial dose 10mg/day
rosuvastatin adverse effects
insomnia, confusion, liver failure, vomit, heart burn, anemia, leukopenia, thrombocytopenia, rhabmyolysis