Statin Flashcards

1
Q

Atorvastatin trade name

A

lipitor

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2
Q

atorvastatin drug classification

A

antilipidemic, statin

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3
Q

atoravastatin expected effect

A

inhibit HMG- CoA enzyme to reduce cholesterol synthesis. High doses lead to plaque regression

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4
Q

atoravastatin why use

A

hypercholesterolemia
dysbetalipoproteinemia
^ triglyceride levels
- prevention CVD by reducing heart risk in those with ^ cholesterol

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5
Q

atoravastatin route of admin

A

PO

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6
Q

atoravastatin dosages

A

10-80mg/day

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7
Q

atoravastatin adverse effects

A

liver dysfunction
pancreatitis
rhabdomyolysis

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8
Q

atoravastatin nursing implications

A

hypercholesterolemia (diet, triglyceride levels)
hepatic studies
renal studies
bowel status (constipation)
rhabdomyolysis (muscle pain, CPK)
evaluate: decrease LDL, cholesteril, CAD, triglycerides, ^ HDL
teach: bloodwork, stop smoking, diet, exercise, eye exam, photosensitivity
NOT TO TAKE IF PREGNANT OR BREASTFEEDING, NO ALCOHOL

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9
Q

rosuvastain trade name

A

crestor

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10
Q

rosuvastatin drug classification

A

statin

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11
Q

rosuvastatin expected effect

A

inhibit HMG- CoA reductase enzyme which reduces cholesterol synthesis

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12
Q

rosuvastatin route of admin

A

PO

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13
Q

rosuvastatin why use

A
  • hypercholesterolemia
  • CVD
  • MI, stroke
  • slow progression atherosclerosis
  • ^ triglyceride levels
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14
Q

rosuvastatin dosages

A

MI/ stroke: 5-20mg
atherosclerosis: 20mg/day
hypercholesterolemia (family): 20mg/day max 40
hypercholesterolemia: 5-40mg, initial dose 10mg/day

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15
Q

rosuvastatin adverse effects

A

insomnia, confusion, liver failure, vomit, heart burn, anemia, leukopenia, thrombocytopenia, rhabmyolysis

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16
Q

rosuvastatin nursing implications

A

rhabdomyolysis: muscle pain, tender, CPK

- do not take if pregnant/ breast feeding