Antidysrhythmics Flashcards
Procainamide hydrochloride trade name
procainamide
procainamide hydrochloride class
antidysrhythmic
procainamide hydrochloride expected effect
depress excitability of cardiac muscle to electrical stimulation and slows conduction in atrium, bundle of His, increases refractory period.
Sodium channel blocker, slowing conduction sodium ions thru sodium channels. Blocking these channels slows conductivity & prolongs action potential & refractory period. Result is decrease excitability and impulse conduction of atria & ventricles
why use procainamide hydrochloride
ventricular dysrhythmia
procainamide hydrochloride dose
20-50mg/min (17mg/kg)
procainamide hydrochloride route admin
IV, IM
procainamide hydrochloride adverse effects
skin sores, hives, fever, chills
- heart block, circa collapse, angioedema, tornadoes de points, agranulocytosis
procainamide hydrochloride nursing implications
- use ECG to check PR-QRS segments
- blood levels & CBC
- vitals
- respiratory status (rate, rhythm, crackles)
- toxicity (confusion, nausea, vomit, drowsy)
- CNS effects (dizzy, confused, seizure)
propanolol trade names
inderal, inderal LA, Innopran
propranolol expected effect
non selective beta blockers with negative inotropic, chronotropic, dromotropic properties
why use propanolol
angina, hypertension, dysrhythmias, migraine, cyanotic spells from aortic stenosis, MI
dosage of propanolol
PO: 10-30mg tid qid, IV 1-3mg give 1mg/min may report after 2 mins & q4h intervals
propanolol routes admin
PO, IV
propanolol adverse effects
bradycardia, CHF, pulmonary edema, dysrhythmias, thrombocytopenia, Stevens Johnson syndrome, toxic epidermal necrolysis
propanolol nursing implications
- no abrupt discontinuation
- monitor with ECG
- note angina pain (duration, time started)
- fluid overload (edema)
- tolerance
- headache, light head, low BP= lower dose