Antihistamine Flashcards
diphenhydramine trade names
allerdryl, benadryl, zzzquil
diphenhydramine drug class
antihistamine
diphenhydramine expected effect
decrease allergic response by competing with histamine for receptor site by blocking histamine.
Act on blood, GI, respiratory system by competing histamine for H receptor site which decreases allergy response by blocking histamine
diphenhydramine why use
allergy, rhinitis, motion sickness, antiparkinsonism, nighttime sedation, infant colic, insomnia, cough
diphenhyramine route admin
PO IM IV
diphenhydramine dose
PO 25-50 q4-6 to max 300mg
IV IM 10-50mg to max 300mg
diphendydramine adverse effects
seizure, thrombocytopenia, agranulocytosis, anemia, anaphylaxis
diphenhydramine nursing implications
urine patterns, CBC, respirations
cetirizine trade names
all day allergy, all day allergy childrens, reaction, Zyrtec, Zyrtec children
cetirizine drug class
antihistamine
cetirizine why use
rhinitis, allergy, chronic idiopathic urticaria
cetirizine expected effects
act on blood, GI, respiratory by competing histamine for H1 receptor site. Allergic response decreased by blocking pharm effects of histamine
cetirizine route admin
PO
cetirizine adverse effects
headache, drowsy, fatigue, dry mouth, thickened bronchial secretions
cetirizine dose
rhinitis/ urticaria: 5-10mg
hay fever/ allergies: 10mg
renal/ hepatic dose: 5mg
cetirizine nursing implications
assess allergy, no driving alcohol or sunlight, sugarless gum candy, sip water to prevent dry mouth, no breastfeed
fexofenadine trade name
allegra
fexofenadine drug class
antihistamine
fexofenadine why use
rhinitis, allergy, chronic idiopathic urticaria
fexofenadine expected effect
act on blood, GI, respiratory system by competing with H1 receptor site. Decreases allergic response by blocking pharm effects of histamine, less sedating.
fexofenadine route admin
PO
fexofenadine dose
60mg bid or 180mg
fexofenadine adverse effects
dysrhythmias, penias
fexofenadine nursing implications
assess: allergies, I &O, bronchial secretions (increase fluids)
evaluate: no running or congested nose
teach: no driving or hazardous activity, no alcohol or depressants, do not exceed recommended dose or dysrhythmias occur