Antiemetic

Question 1

dolasetron trade name

Answer 1

anzemet

Question 2

dolasetron expected effect

Answer 2

prevent nausea, vomit by blocking it in small intestine

Question 3

why use dolasetron

Answer 3

prevent postop nausea and vomit

Question 4

dolasetron route admin

Answer 4

IV PO

Question 5

dolasetron adverse effects

Answer 5

dysrhythmias, ventricular tachycardia/ fibrillation, QT prolongation, cariac arrest, bronchospasm

Question 6

dolasetron doses

Answer 6

IV 12.5mg before start anesthesia

PO 100mg 2h before surgery

Question 7

dolasetron nursing implications

Answer 7

assess: hypersensitivity, cardiac conduction, electrolyte imbalances, dysrhythmias
evaluate: therapeutic response
teach: report typical side effect problems
may cause headache so use anagesic

Question 8

dimenhydrinate trade names

Answer 8

dramamine, driminate, gravol

Question 9

dimenhydrinate classes

Answer 9

antiemetic, antihistamine, anticholinergic

Question 10

dimenhydrinate why use

Answer 10

motion sickness, nausea, vomit, vertigo

Question 11

dimenhydrinate expected effect

Answer 11

compete with histamine for H1 receptors in GI, blood, rest tract; anticholinergic, less vestibular sim, block chemoreceptor trigger

Question 12

dimenhydrinate dose

Answer 12

PO 50-100 q4h

IM IV 50mg q4h

Question 13

dimenhydrinate route admin

Answer 13

PO IM IV elixir

Question 14

dimenhydrinate adverse effects

Answer 14

ANAPHYLAXIS, dry mouth, drowsy, dry mouth, hypotension, constipation

Question 15

dimenhydrinate nursing implications

Answer 15

check BP, vitals,
signs toxicity mask symptoms of disease
avoid hazards/ alert activities
avoid alcohol depressants

Question 16

meclizine trade names

Answer 16

antivert, bonine, dramamine less drowsy formula

Question 17

meclizine class

Answer 17

antiemetic, antihistamine, anticholinergic

Question 18

meclizine expected effect

Answer 18

act centrally by blocking chemo zone which acts on vomit centre

Question 19

meclizine why use

Answer 19

vertigo, motion sickness

Question 20

meclizine route admin

Answer 20

PO

Question 21

meclizine doses

Answer 21

vertigo: 25-100mg

motion sickness: 25-50mg 1h before travelling

Question 22

meclizine adverse effects

Answer 22

ANAPHYLAXIS, drowsy, urine retention, hypotension, constipation, blurred vision

Question 23

meclizine nursing implications

Answer 23

alert: signs toxicity other products mask symptoms disease
may cause false positive allergy
avoid alcohol, depressants, no breast feeding

Question 24

metoclopramide trade names

Answer 24

Apo-metoclop, metozolv, reglan

Question 25

metoclopramide drug classes

Answer 25

antiemetic, cholinergic

Question 26

metoclopramide expected effect

Answer 26

contract gastric muscle in upper GI tract by enhancing tissues response to ACh, relax pyloric & duodenal segments, increase peristalsis without stimulating secretions & block dopamine in chemo trigger zone in CNS

Question 27

why use metoclopramide

Answer 27

prevent nausea, vomit from chemo, radiation, delayed gastric emptying, GERD

Question 28

metoclopramide route admin

Answer 28

PO IV

Question 29

metoclopramide adverse effects

Answer 29

sucide, neuroleptic malignant, tardive dyskinesia, penias

Question 30

metoclopramide doses

Answer 30

nausea vomit: 1-2mg/kg IV 30 min befor chemo, q2h x 2 doses then q3h x 3 doses

GERD
PO 10-15 mg qid 30 mins before meals and bed

diabetic gastroparesis
PO 10mg 30min before meals, at bed x 2-8 wk

Question 31

metoclopramide black box warning

Answer 31

EPS, tardive dyskinesia

Question 32

metoclopramide nursing implications

Answer 32

neuroleptic malignant syndrome, avoid driving & hazardous activities, avoid alcohol & CNS depressants