Oral Hypoglycemic

Question 1

metformin trade name

Answer 1

glucophage

Question 2

metformin drug class

Answer 2

antihyperglycemic, buguanide, antidiabetic

Question 3

metformin expected effect

Answer 3

inhibit hepatic glucose production & ^ sensitivity in peripheral tissue to insulin

Question 4

metformin dose

Answer 4

500mg PO BID then 500mg weekly up to 2000mg daily

Question 5

metformin route

Answer 5

PO

Question 6

metformin adverse effects

Answer 6

lactic acidosis, thrombocytopenia, vertigo, vomit, diarrhea

Question 7

metformin nursing implications

Answer 7

do not give with radiologic contrast media > renal failure
no dofetilide > lactic acidosis
limit alcohol bc ^ lactic acidosis and low blood sugar
metformin can pass in breast milk
take with food to lower side effects

Question 8

glyburide trade name

Answer 8

DiaBeta

Question 9

glyburide drug class

Answer 9

antidiabetic, sulfonylureas

Question 10

glyburide route admi

Answer 10

PO

Question 11

glyburide expected effect

Answer 11

cause beta cells of pancreas to release insulin leading to drop in blood glucose; may improve insulin binding to insulin receptors & increase number insulin receptors

Question 12

glyburide dose

Answer 12

1.25-5mg single dose then increase at weekly intervals up to 20mg day

Question 13

glyburide adverse effects

Answer 13

typical side effects, rash skin pruritus eczema, hypoglycaemia, hepatoxicity, jaundice, hepatic failure, penias

Question 14

glyburide nursing considerations

Answer 14

hypo/hyper runs after meals
check blood sugar, CBC
evauluate: lower sugar, decrease polyuria, polydipsia
teach: symptoms jaundice, blood glucose testing, take in morning to prevent hypo at night, photosensitivity, diabetes lifelong, food diet plan and emergency sugar packets, report bleeding brushing weight gain edema