Antianginals

Question 1

Carvedilol trade names

Answer 1

Coreg, Coreg CR

Question 2

carvedilol drug classification

Answer 2

antianginal

Question 3

carvedilol expected effect

Answer 3

decrease cardiac output, exercise & reflex orthostatic tachycardia by causing vasodilation & reducing peripheral vascular resistance

Question 4

why use carvedilol

Answer 4

hypertension, CHF, cardiomyopathy, MI

Question 5

carvedilol route of admin

Answer 5

PO

Question 6

carvedilol dosages

Answer 6

BP 6.25 bid, then ^ 12.5 BID
CHF 3.125 bid then 6.25 bid
post MI 6.25 bid, then 12.5bid, to 25bid

Question 7

carvedilol adverse effects

Answer 7

bradycardia, AV block, pulmonary edema, CHF, lung edema, bronchospasm, thrombocytopenia

Question 8

carvedilol BLACK BOX

Answer 8

Abrupt discontinuation, do not discontinue before surgery, taper over 1-2 weeks, life threatening dysrhythmias occur

Question 9

isosorbide dinitrate trade names

Answer 9

Apo- ISDN, Isordil, IsoDitrate, Dilatrate SR, Isochron

Question 10

isosorbide dinitrate drug classification

Answer 10

antianginal

Question 11

isosorbide dinitrate expected effect

Answer 11

relaxes vascular smooth muscle which decrease preload & after load, which decreases left ventricular end diastolic pressure, systemic vascular resistance & reduce cardiac oxygen demand

Question 12

isosorbide dinitrate why use

Answer 12

chronic stable angina pectoris

Question 13

isosorbide dinitrate route of admin

Answer 13

PO, SL

Question 14

isosorbide dinitrate dosage

Answer 14

PO 5-20mg BID TID (Maintain 10-40)
SL 2.5-5mg TID
extended release 40-80mg, max 160/day

Question 15

isosorbide dinitrate adverse effects

Answer 15

anemia, methemoglobinemia

Question 16

isosorbide dinitrate nursing implications

Answer 16

assess angina & methemoglobinemia
check BP, pulse, respirations
do not discontinue abruptly
no alcohol/ hazardous activities
move slowly to prevent orthostatic hypotension

Question 17

nitroglycerine trade names

Answer 17

nitro-time, nitrogard SR, Nitro- BID, Reactive, Nitrostat, Nitrolingual, NitroMist, Nitro- Dur

Question 18

nitroglycerine drug classification

Answer 18

antianginal, coronary vasodilator

Question 19

nitroglycerine expected effect

Answer 19

decrease angina pain, decrease preload & after load, decrease left ventricle end diastolic pressure, systemic vessel resistance, dilate arteries veins,coronary arteries

Question 20

nitroglycerine why use

Answer 20

chronic stable angina
CHF
MI
angina
controlled hypotension during surgery

Question 21

routes of admin for nitroglycerine

Answer 21

SL, PO, topical, IV, transdermal patch, rectal, nasal

Question 22

nitroglycerine adverse effects

Answer 22

collapse & palpitations, postural hypotension

Question 23

nitroglycerine nursing implications

Answer 23

assess: pain, pulse, BP
teach: how to take routes, move slowly to avoid fainting, take med before strenuous activity
- light headed, low BP may need lower dose

Question 24

nitroglycerine black box warnings

Answer 24

alcohol can cause hypotension & circa collapse

erectile dysfunction lead to hypotension & death

Question 25

nitroglycerine dosages

Answer 25

see paper