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Nursing 2P16 > Proton Pump Inhibitors > Flashcards

Proton Pump Inhibitors Flashcards

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1
Q

Pantoprazole trade names

A

Panto, Pantoloc, Protonix, Protonix IV, Tecta

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2
Q

Pantoprazole drug classification

A

proton pump inhibitor

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3
Q

pantoprazole expected effect

A

suppress gastric secretions by inhibiting H/K ATPase enzyme system in gastric parietal cell. Gastric acid inhibitor bc blocks final step of acid production

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4
Q

why use pantoprazole

A

GERD, severe erosive esophagitis, pathologic hypersecretion (Zollinger- Ellison)

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5
Q

pantoprazole adverse effects

A 
headache, insomnia, fatigue
diarrhea, abdominal pain, flatulence 
myalgia, rhabdomyolysis
Stevems Johnson syndrome, toxic epidermal necrolysis, angioedema
weight gain/ loss, hyperglycemia
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6
Q

pantoprazole route of admin

A

PO, NG, IV

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7
Q

pantoprazole nursing implications

A
  • watch for hypersensitivity
  • serious skin disorders
  • precaution for breast feeding, pregnant, children
  • rhabdomyolysis (muscle pain, ^ CPK)
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8
Q

pantoprazole dosages

A

GERD PO 40mg/ day
erosive esophagitis IV & PO 40mg/day
hypersecretory conditions PO 40mg BID, IV 80mg q12h, max 240mg/day
ulcers 40mg BID

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9
Q

omeprazole trade names

A

Losec, Prilosec

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10
Q

omeprazole drug classification

A

proton pump inhibitor

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11
Q

omeprazole expected effect

A

suppress gastric secretion by inhibiting H/K ATPase enzyme in gastric parietal cells, Blocks final step acid production

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12
Q

omeprazole why use

A

GERD, erosive esophagitis, hypersecretory conditions (Zollinger- Ellison), mastocytosis, duodenal ulcers

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13
Q

omeprazole route of admin

A

PO, NG

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14
Q

omeprazole dosages

A

GERD/ erosive esophagitis 20mg/ day PO
hypersecretory conditions 60mg/ day, up to 120mg, no single dose over 80mg
duodenal ulcer 20mg daily, 40mg if H Pylori
gastric ulcer 40mg/ day

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15
Q

omeprazole adverse effects

A

LIFE THREATENING hepatic failure & pneumonia

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16
Q

omeprazole nursing implications

A 
precaution: children, pregnancy
GI: bowel sounds, pain, swelling
electrolyte imbalance
hepatic enzymes (CBC, vitamin B12)
CBC
discontinue if black tarry stools, abdominal cramps

Nursing 2P16 (20 decks)

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