SSRI_Side_Effects_Interactions_Flashcards

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1
Q

Which SSRIs are currently preferred?

A

Citalopram and fluoxetine are currently the preferred SSRIs.

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2
Q

Which SSRI is useful post-MI?

A

Sertraline is useful post-MI.

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3
Q

Which SSRI is the drug of choice in children?

A

Fluoxetine is the drug of choice in children.

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4
Q

What are common side effects of SSRIs?

A

Common side effects of SSRIs include GI upset, GI bleeding, and increased anxiety and agitation soon after starting.

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5
Q

What should be done if NSAIDs are used with SSRIs?

A

If NSAIDs are used with SSRIs, they should be given with a PPI.

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6
Q

What should patients be warned about when starting SSRIs?

A

Patients should be warned about increased anxiety and agitation soon after starting SSRIs, which usually occurs in the first 2 weeks and tends to settle.

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7
Q

Which SSRIs have a higher propensity for drug interactions?

A

Fluoxetine and paroxetine have a higher propensity for drug interactions.

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8
Q

Which SSRIs are associated with a dose-dependent increase in QTc?

A

Citalopram and escitalopram are associated with a dose-dependent increase in QTc.

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9
Q

What are the maximum daily doses of citalopram for adults, those over 65 years, and those with hepatic impairment?

A

The maximum daily doses of citalopram are 40 mg for adults, 20 mg for those over 65 years, and 20 mg for those with hepatic impairment.

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10
Q

What should be done if NSAIDs or aspirin are used with SSRIs?

A

If NSAIDs or aspirin are used with SSRIs, they should be given with a PPI.

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11
Q

What is the recommended action regarding SSRIs when a patient is on warfarin or heparin?

A

When a patient is on warfarin or heparin, SSRIs should be avoided, and mirtazapine should be considered.

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12
Q

What should be avoided when SSRIs are used with triptans?

A

SSRIs should be avoided when used with triptans.

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13
Q

What is the risk of using MAOIs with SSRIs?

A

There is a risk of serotonin syndrome when MAOIs are given at the same time as SSRIs.

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