Benzodiazepines_Flashcards
What is the mechanism of action of benzodiazepines?
Benzodiazepines enhance the effect of GABA by increasing the frequency of opening of the chloride ion channel.
What are the uses of benzodiazepines?
Benzodiazepines are used as a sedative, hypnotic, anxiolytic, anticonvulsant, and muscle relaxant.
For how long should benzodiazepines be used?
Benzodiazepines should not be used for longer than 2-4 weeks.
What are the features of benzodiazepine withdrawal?
Features of benzodiazepine withdrawal include insomnia, irritability, anxiety, tremor, loss of appetite, tinnitus, perspiration, perceptual disturbance, and seizures.
How do barbiturates differ in their mechanism of action compared to benzodiazepines?
Barbiturates differ in their mechanism of action by increasing the duration of chloride channel opening.
