SSRI_Side_Effects_Flashcards
What are the most common side-effects of SSRIs?
Gastrointestinal symptoms are the most common side-effects of SSRIs.
What is the risk associated with gastrointestinal bleeding in patients taking SSRIs?
There is an increased risk of gastrointestinal bleeding in patients taking SSRIs.
What should be prescribed if a patient taking SSRIs is also taking an NSAID?
A proton pump inhibitor should be prescribed if a patient taking SSRIs is also taking an NSAID.
What electrolyte imbalance can be caused by SSRIs?
SSRIs can cause hyponatraemia.
What should patients be vigilant for after starting an SSRI?
Patients should be vigilant for increased anxiety and agitation after starting an SSRI.
Which SSRIs have a higher propensity for drug interactions?
Fluoxetine and paroxetine have a higher propensity for drug interactions.
What warning did the MHRA release regarding citalopram in 2011?
The MHRA released a warning in 2011 that citalopram and escitalopram are associated with dose-dependent QT interval prolongation.
What are the conditions under which citalopram should not be used?
Citalopram should not be used in patients with congenital long QT syndrome, known pre-existing QT interval prolongation, or in combination with other medicines that prolong the QT interval.
What is the maximum daily dose of citalopram for adults, patients older than 65 years, and those with hepatic impairment?
The maximum daily dose of citalopram is 40 mg for adults, 20 mg for patients older than 65 years, and 20 mg for those with hepatic impairment.
What does NICE advise regarding the use of SSRIs with NSAIDs?
NICE advises ‘do not normally offer SSRIs’ with NSAIDs, but if given, co-prescribe a proton pump inhibitor.
What does NICE recommend regarding the use of SSRIs with warfarin or heparin?
NICE recommends avoiding SSRIs with warfarin or heparin and considering mirtazapine.
What does NICE advise regarding the use of SSRIs with aspirin?
NICE advises avoiding SSRIs with aspirin.
What is the recommendation for SSRIs and triptans?
SSRIs should be avoided with triptans.
When should patients normally be reviewed by a doctor after initiating antidepressant therapy?
Patients should normally be reviewed by a doctor after 2 weeks of initiating antidepressant therapy.
When should patients under the age of 30 years or at increased risk of suicide be reviewed after starting antidepressant therapy?
Patients under the age of 30 years or at increased risk of suicide should be reviewed after 1 week of starting antidepressant therapy.