maoi_flashcards

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1
Q

What do monoamine oxidase inhibitors (MAOIs) metabolize in the presynaptic cell?

A

Serotonin and noradrenaline.

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2
Q

What are examples of non-selective monoamine oxidase inhibitors?

A

Tranylcypromine, phenelzine.

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3
Q

What are non-selective MAOIs used to treat?

A

Atypical depression and other psychiatric disorders.

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4
Q

Why are non-selective MAOIs not used frequently?

A

Due to their side-effects.

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5
Q

What are the adverse effects of non-selective MAOIs?

A

Hypertensive reactions with tyramine-containing foods and anticholinergic effects.

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6
Q

What foods can cause hypertensive reactions with non-selective MAOIs?

A

Cheese, pickled herring, Bovril, Oxo, Marmite, broad beans.

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7
Q

What type of effects do non-selective MAOIs have aside from hypertensive reactions?

A

Anticholinergic effects.

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