maoi_flashcards
What do monoamine oxidase inhibitors (MAOIs) metabolize in the presynaptic cell?
Serotonin and noradrenaline.
What are examples of non-selective monoamine oxidase inhibitors?
Tranylcypromine, phenelzine.
What are non-selective MAOIs used to treat?
Atypical depression and other psychiatric disorders.
Why are non-selective MAOIs not used frequently?
Due to their side-effects.
What are the adverse effects of non-selective MAOIs?
Hypertensive reactions with tyramine-containing foods and anticholinergic effects.
What foods can cause hypertensive reactions with non-selective MAOIs?
Cheese, pickled herring, Bovril, Oxo, Marmite, broad beans.
What type of effects do non-selective MAOIs have aside from hypertensive reactions?
Anticholinergic effects.