Spore Forming Bacilli Flashcards

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1
Q

Spore-Forming Bacilli

A

Bacillus anthracis
Clostridium botulinum
Clostridium perfringens
Clostridium tetani

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2
Q

Bacillus anthracis Diseases
Spore-Forming Bacilli

A
  • Skin Anthrax/Skin Cutaneous Infection: Non-pus Lesions called escars leave a ring of small blisters that surround a dark center
  • Pulmonary Anthrax/ Wool-sorter’s Disease/Inhalation Anthrax
  • Typhoidal Anthrax/ Ingestion Anthrax
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3
Q

Bacillus anthracis Characteristics
Spore-Forming Bacilli

A
  • Rod Shaped
  • Endospore
  • Gram-Positive: cell wall is thick; purple when stained; killed by penicillin
  • Obligate Aerobic: microorganisms that can only live in the presence of oxygen, because they need oxygen to metabolize sugars
  • Single or in chains
  • Non-motile
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4
Q

Bacillus anthracis Virulence
Spore-Forming Bacilli

A
  • Endospore
  • Capsule (resists phagocytosis)
  • Exotoxin
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5
Q

Bacillus anthracis Portals of Entry and Exit
Spore-Forming Bacilli

A
  • Broken Skin: Direct contact with infected animal
  • Respiratory Tract: Inhalation of pneumonic form
  • GI Tract: Ingestion of contaminated meat
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6
Q

Bacillus anthracis Modes of Transmission
Spore-Forming Bacilli

A
  • Direct: Directly handling infected animal
  • Indirect: Inhalation
  • Indirect: Ingestion of contaminated meat
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7
Q

Clostridium botulinum Diseases
Spore-Forming Bacilli

A
  • Food-borne Botulism: flaccid paralysis, cardiac & respiratory failure, nausea, double or blurred vision
  • Infant Botulism
  • Wound Botulism: wounds are infected with spores
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8
Q

Clostridium botulinum Characteristics
Spore-Forming Bacilli

A
  • Rod Shaped
  • Endospore
  • Gram-Positive: cell wall is thick; purple when stained; killed by penicillin
  • Obligate Anaerobe: microbes that can only survive in an environment devoid of oxygen
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9
Q

Clostridium botulinum Virulence
Spore-Forming Bacilli

A
  • Endospore
  • Neurotoxin (causes Flaccid Paralysis: weakness of muscles to non-movement)
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10
Q

Clostridium botulinum Portals of Entry and Exit
Spore-Forming Bacilli

A
  • Broken Skin: spores enter wounds
  • GI Tract: Ingestion of contaminated meat/food
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11
Q

Clostridium botulinum Modes of Transmission
Spore-Forming Bacilli

A
  • Indirect: Ingestion of contaminated meat
  • Indirect: Wound contamination
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12
Q

Clostridium perfringens Diseases
Spore-Forming Bacilli

A
  • Gas Gangrene/Myonecrosis: Bacteria gather in an injury or surgical wound that has no blood supply.
    The bacterial infection produces toxins that release gas and cause tissue death (antemortem)
  • Tissue Gas: Postmortem form of tissue gas; can spread through instruments
  • Food Poisoning
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13
Q

Clostridium perfringens Characteristics
Spore-Forming Bacilli

A
  • Rod Shaped
  • Endospore
  • Gram-Positive: cell wall is thick; purple when stained; killed by penicillin
  • Obligate Anaerobe: microbes that can only survive in an environment devoid of oxygen
  • Saprophyte: organisms that survive on dead or decaying organic matter
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14
Q

Clostridium perfringens Virulence
Spore-Forming Bacilli

A
  • Endospore
  • Enzymes: Hyaluronidae allows bacteria into the body’s connective tissues
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15
Q

Clostridium perfringens Portals of Entry and Exit
Spore-Forming Bacilli

A
  • Indirect: Fomite contamination
  • Indirect: Ingestion of contaminated meat/food
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16
Q

Clostridium perfringens Modes of Transmission
Spore-Forming Bacilli

A
  • Indirect: Ingestion of contaminated meat
  • Indirect: Wound contamination
17
Q

Clostridium tetani Diseases
Spore-Forming Bacilli

A
  • Tetanus/Lockjaw: prevents muscle relaxation,rigid paralysis, asphyxiation (from muscle tensing)
18
Q

Clostridium tetani Characteristics
Spore-Forming Bacilli

A
  • Rod Shaped
  • Endospore
  • Gram-Positive: cell wall is thick; purple when stained; killed by penicillin
  • Obligate Anaerobe: microbes that can only survive in an environment devoid of oxygen
19
Q

Clostridium tetani Virulence
Spore-Forming Bacilli

A
  • Endospore
  • Neurotoxin (causes Rigid Paralysis)
20
Q

Clostridium tetani Portals of Entry and Exit
Spore-Forming Bacilli

A

Broken Skin: spores enter wounds

21
Q

Clostridium tetani Modes of Transmission
Spore-Forming Bacilli

A
  • Indirect: Non-Communicable
  • Indirect: Broken Skin with deep puncture wounds get infected be contaminated soil