Spiral Bacteria Flashcards
Spiral Bacteria (Spirochetes)
Gram-negative
unicellular
- Vibrio cholerae
- Treponema pallidum
- Borrelia burgdorferi
- Leptospira interrogans
- Campylobacter jejuni
Vibrio cholerae Diseases
Spiral Bacteria
- Asiatic cholera
- Rice Water Stool: whitish color to feces
Vibrio cholerae Characteristics
Spiral Bacteria
- Spiral, comma, or curve shaped
- Causes severe dehydration, which leads to organ failure
- Foodborne illness
Vibrio cholerae Virulence
Spiral Bacteria
- Cholera toxin
(blocks water absorption, bicarbonates, chlorides, electrolytes etc from entering the intestinal lining (toxin causes the body to not absorb water/nutrients)
Vibrio cholerae Portals of Entry and Exit
Spiral Bacteria
- Broken Skin: Through burn wounds
- GI Tract: Ingestion of contaminated food/water
Vibrio cholerae Modes of Transmission
Spiral Bacteria
- Indirect: Ingestion of contaminated food/water
Treponema pallidum Diseases
Spiral Bacteria
-Exclusively found in humans
-
Syphilis
- Acquired Syphilis: Received through direct sexual contact
- Congenital Syphilis: Infected pregnant woman passes infection to unborn child
- 4 Stages of Syphilis
- Primary Syphilis: Chancre sore form (small hard ulcers)
- Secondary Syphillis: Skin rashes form on the hands and feet
- Latent/Hidden: Symptoms disappear
- Tertiary Syphilis: Gummas form (rubber-like lesions); other severe symptoms including dementia, madness, tumors occur. People usually do not get to this stage because of modern medicine
Treponema pallidum Characteristics
Spiral Bacteria
- Spiral shaped
- Spirochete
Treponema pallidum Virulence
Spiral Bacteria
- Teflon pathogen: named this because the body can not provide an effective defense against it
- Crosses the placenta
- Enzymes
Treponema pallidum Portals of Entry and Exit
Spiral Bacteria
- Placenta
- GI Tract
- Sexual Contact
Treponema pallidum Modes of Transmission
Spiral Bacteria
- Direct: STD acquired through direct sexual contact
- Direct: Congenital/placental transmission
Borrelia burgdorferi Diseases
Spiral Bacteria
Lyme Disease/ Lyme Borreliosis: Creates a Bull’s eye rash
Borrelia burgdorferi Characteristics
Spiral Bacteria
- Spiral shaped
- Spirochete
Borrelia burgdorferi Virulence
Spiral Bacteria
Endoflagella/Axial Filamanets (allows the pathogen to rotate in a corkscrew motion)
Borrelia burgdorferi Portals of Entry and Exit
Spiral Bacteria
Broken Skin: Tick bite allows pathogen to enter body
Borrelia burgdorferi Modes of Transmission
Spiral Bacteria
Indirect: Biological Insect Transmission from an infected Deer Tick
Leptospira interrogans Diseases
Spiral Bacteria
- Leptospirosis/Infectious Jaundice: Biphasic (2-part)disease that starts with flu-like symptoms and later progresses into liver damage, and renal failure
- Weil’s Disease: Advanced case of severe liver and kidney damage; secondary disease to leptospirosis
Leptospira interrogans Characteristics
Spiral Bacteria
- Spiral shaped
- Spirochete
- Zoonosis
Leptospira interrogans Virulence
Spiral Bacteria
High lipid content in bacterial cell wall
Leptospira interrogans Portals of Entry and Exit
Spiral Bacteria
- Broken Skin
- GI Tract: Ingestion
Leptospira interrogans Modes of Transmission
Spiral Bacteria
Indirect: Ingestion of contaminated water (possibly from animal urine)
Campylobacter jejuni Diseases
Spiral Bacteria
- Campylobacteriosis/Campylobacter gastroenteritis
- Guillian-Barre Syndrome (GBS): rare condition that causes temporary paralysis
Campylobacter jejuni Characteristics
Spiral Bacteria
- Spiral-shaped or vibrio (comma or curved)
- Non-spore forming
- Gram-Negative
- Food-borne illness
Campylobacter jejuni Virulence
Spiral Bacteria
- Enterotoxin
- Flagella
Campylobacter jejuni Portals of Entry and Exit
Spiral Bacteria
GI Tract: Ingestion
Campylobacter jejuni Modes of Transmission
Spiral Bacteria
- Indirect: Ingestion of contaminated food/ water