Small Gram Negative Bacilli Flashcards

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1
Q

Small Gram-Negative Bacilli

A
  • Bordatella pertussis
  • Haemphilus influenzae
  • Yersinia Pestis
  • Francisella tularensis
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2
Q

Bordatella pertussis Diseases
Small Gram-Negative Bacilli

A
  • Whooping Cough/Pertussis: Convulsive, painful coughing

Stage 1: Incubation Stage: no outward symptoms
Stage 2: Catarrhal Stage: Common cold-like symptoms
Stage 3:Paroxysmal Stage: Spasmodic or convulsive coughing; ciliary escalator in lungs stop; peak of the disease
Stage 4: Convalescent Stage: Recovery

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3
Q

Bordatella pertussis Characteristics
Small Gram-Negative Bacilli

A
  • Small Gram-Negative Bacilli
  • Rod Shaped (coccobacillus)
  • Gram-Negative: cell wall is thin; pink when stained’ penicillin-resistant
  • Obligate Aerobic: microorganisms that can only live in the presence of oxygen, because they need oxygen to metabolize sugars
  • High Risk for Children
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4
Q

Bordetella pertussis Virulence
Small Gram-Negative Bacilli

A
  • Capsule (resists phagocytosis)
  • Toxins
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5
Q

Bordetella pertussis Portal of Entry and Exit
Small Gram-Negative Bacilli

A

Respiratory Tract: Droplet transmission or inhalation; exit through coughing or snot

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6
Q

Bordetella pertussis Modes of Transmission
Small Gram-Negative Bacilli

A
  • Direct: Droplet transmission
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7
Q

Haemophilus influenzae Diseases
Small Gram-Negative Bacilli

A
  • Bacterial Influenzal Meningitis:
  • Hib Meningitis
  • Haemophilus influenzae Meningitis

Meningitis is an infection of the meninges, membranes covering the brain and spinal cord

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8
Q

Haemophilus influenzae Characteristics
Small Gram-Negative Bacilli

A
  • Small Gram-Negative Bacilli
  • Rod Shaped (bacillus)
  • Facultative Anaerobe: prefer oxygen but can go without it if forced to
  • Gram-Negative: cell wall is thin; pink when stained; penicillin-resistant
  • Non-motile
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9
Q

Haemophilus influenzae Virulence
Small Gram-Negative Bacilli

A

Capsule (resists phagocytosis)

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10
Q

Haemophilus influenzae Portals of Entry and Exit
Small Gram-Negative Bacilli

A

Respiratory Tract: Droplets or inhalation; exit through coughing or snot

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11
Q

Haemophilus influenzae Modes of Transmission
Small Gram-Negative Bacilli

A

Direct: Droplet transmission

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12
Q

Yersinia Pestis Diseases
Small Gram-Negative Bacilli

A
  • Bubonic Plague/Black Death: Infection of the lymphatic system; Lesions called BUBOS form
  • Septicemic Plague: Infection in the blood stream
  • Pneumonic Plague

Both the septicemic and pneumonic plagues can be secondary infections from the bubonic plague or be spread on their own

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13
Q

Yersinia Pestis Characteristics
Small Gram-Negative Bacilli

A
  • Small Gram-Negative Bacilli
  • Rod Shaped (bacillus)
  • Facultative Anaerobe: prefer oxygen but can go without it if forced to
  • Gram-Negative: cell wall is thin; pink when stained; penicillin-resistant
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14
Q

Yersinia Pestis Virulence
Small Gram-Negative Bacilli

A

Capsule (resists phagocytosis)

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15
Q

Yersinia Pestis Portals of Entry and Exit
Small Gram-Negative Bacilli

A
  • Broken Skin: through an infected animal bite (Bubonic Plague)
  • Respiratory Tract: Droplets/coughing (Pneumonic Plague)
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16
Q

Yersinia Pestis Modes of Transmission
Small Gram-Negative Bacilli

A
  • Direct: Droplet transmission
  • Indirect: Bite from an Insect vector (rat flea) or Biological vector (an animal/rat bitten by a rat-flea)
17
Q

Francisella tularensis Diseases
Small Gram-Negative Bacilli

A
  • Tularemia/Rabbit Fever/Deerfly Fever
  • Skin Infection
  • GI Infection
  • Pneumonic Infection
18
Q

Francisella tularensis Characteristics
Small Gram-Negative Bacilli

A
  • Small Gram-Negative Bacilli
  • Rod Shaped (bacillus)
  • Facultative Anaerobe: prefer oxygen but can go without it if forced to
  • Gram-Negative: cell wall is thin; pink when stained; penicillin-resistant
  • Non-motile
19
Q

Francisella tularensis Virulence
Small Gram-Negative Bacilli

A

Capsule (resists phagocytosis)

20
Q

Francisella tularensis Portals of Entry and Exit
Small Gram-Negative Bacilli

A
  • Skin
  • Respiratory Tract
  • GI Tract
21
Q

Francisella tularensis Modes of Transmission
Small Gram-Negative Bacilli

A
  • Direct: Direct Contact with animal host
  • Indirect: Insect vector (deerflies, rabbit lice, ticks)
  • Indirect: Ingestion
  • Indirect: Airborne transmission