Specific Antimicrobial Drugs

Question 1

Which antimicrobial drug is an inhibitor of cell wall synthesis, effective against gram-positive bacteria, is stable in stomach acids, and is given via oral administration?

Answer 1

Penicillin V

Question 2

Which antimicrobial drug is a semisynthetic penicillin, is broad spectrum, and is combined with inhibitor of penicillinase?

Answer 2

Amoxicillin

Question 3

Which antimicrobial drug is anthelmintic, alters plasma membrane permeability, and kills flatworms?

Answer 3

Praziquantel

Question 4

Which antimicrobial drug inhibits synthesis of the mycolic acid in mycobacterium and has little effect on non-mycobacteria?

Answer 4

Isoniazid

Question 5

Which antimicrobial drug is anti-retroviral, inhibits DNA or RNA synthesis, and is a nucleoside analog used in the treatment of HIV?

Answer 5

Zidovudine (AZT)

Question 6

Which antimicrobial drug is the best known aminoglycoside and is used in the alternative treatment of tuberculosis?

Answer 6

Streptomycin

Question 7

Which antimicrobial drug is an antihelminthic drug that inhibits ATP production under aerobic conditions and kills tapeworms?

Answer 7

Niclosamide

Question 8

Which two antimicrobial drugs are antiviral, inhibit entry and fusion, and inhibit neuraminidase on the influenza virus?

Answer 8

Zanamivir and Oseltamivir (tamiflu)

Question 9

Which antimicrobial drug is a competitive inhibitor of the synthesis of essential metabolites, combination is widely used, only 10% is needed when combination is used, and is a sulfonamide?

Answer 9

Trimethoprim-sulfamethoxazole

Question 10

Which antimicrobial drug is produced by Streptomyces, prevents the addition of amino acids to a growing peptide chain, is broad spectrum, is used for chlamydia and rickettsia, and is in animal feed additives?

Answer 10

Tetracyclines

Question 11

Which antimicrobial drug is a synthetic penicillin and is broad spectrum?

Answer 11

Ampicillin

Question 12

Which antimicrobial drug causes injury to the plasma membrane, is effective against gram-negatives, and was one of the only drugs used against pseudomonas?

Answer 12

Polymyxin B

Question 13

Which antimicrobial drug is a synthetic derivative used to control malaria and is an antiprotozoan drug that inhibits DNA synthesis?

Answer 13

Chloroquine

Question 14

Which antimicrobial drug is the best known derivative of the rifamycin family of antibiotics, inhibits synthesis of mRNA, and is used to treat tuberculosis and leprosy?

Answer 14

Rifampin

Question 15

Which antimicrobial drug inhibits the formation of peptide bonds in the growing polypeptide chain by reacting with the 50S portion of the prokaryotic ribosome, is broad spectrum, potentially toxic, and relatively inexpensive?

Answer 15

Chloramphenicol

Question 16

Which antimicrobial drug inhibits influenza A from uncoating?

Answer 16

Amantadine

Question 17

Which antimicrobial drug inhibits cell wall synthesis in the same way that penicillins do and is more widely used than any other B-lactam antibiotic?

Answer 17

Cephalosporins

Question 18

Which antimicrobial drug is an interferon that inhibits the spread of viruses to new cells and is the drug of choice for viral hepatitis?

Answer 18

Alpha interferon

Question 19

Which antimicrobial drug inhibits DNA synthesis, is best known for its use against anthrax, and was widely used in the earliest generation of fluoroquinolones?

Answer 19

Ciprofloxacin

Question 20

Which antimicrobial drug is an aminoglycoside and is especially useful against Pseudomonas infections?

Answer 20

Gentamicin

Question 21

Which two antimicrobial drugs are anthelmintic, inhibits the formation of microtubules in cytoplasm, interferes with absorption of nutrients by the parasite, and are used against intestinal roundworms?

Answer 21

Mebendazole and Albendazole

Question 22

Which antimicrobial drug is a nucleoside analog used for treating herpes infections (especially genital herpes, and is useful in immunosuppressed individuals?

Answer 22

Acyclovir

Question 23

Which antimicrobial drug is an antifungal antibiotic and is produced by streptomyces species in soils?

Answer 23

Amphotericin B

Question 24

Which antimicrobial drug is a semisynthetic penicillin and is very broad spectrum?

Answer 24

Imipenem

Question 25

Which antimicrobial drug is the best macrolide in clinical use, inhibits protein synthesis, and is unable to penetrate gram-negative cell walls?

Answer 25

Erythromycin

Question 26

Which two antimicrobial drugs are widely used antiprotozoal drugs, is the drugs of choice for vaginitis, and are effective in treating giardiasis, amebiasis, and trichomoniasis?

Answer 26

Metronidazole and tinidazole

Question 27

Which 3 antimicrobial drug are antifungal, azoles, inhibit plasma membrane synthesis, are used in treating ringworm, vaginal candidiasis, and systemic mycoses?

Answer 27

Clotrimazole, miconazole, and ketoconazole