Small Group: Diseases of the Lower GI

Question 1

What is DGP?

Answer 1

Deaminated gliadin peptides

Question 2

True or false: all people with tissue transglutaminase antibody are symptomatic.

Answer 2

False. Some people without celiac symptoms have IgA TTg.

Question 3

Ultimately, gluten sensitivity is diagnosed by _____________.

Answer 3

diet exclusion with remission of symptoms

Question 4

Although barium enemas are rarely done in the diagnosis of IBD, what sign is typical of ulcerative coliti?

Answer 4

The “lead pipe” colon, caused by lack of haustra

Question 5

True or false: both forms of IBD can transition to cancer.

Answer 5

True.

Question 6

Why does fat-wrapping occur in Crohn’s but not UC?

Answer 6

Because Crohn’s produces transmural inflammation, so the outer surface – the serosa –gets irritated and fat serves as a protective coat.

Question 7

What two drugs are usually given to treat pseudomembranous colitis?

Answer 7

Flagyl or vancomycin

Question 8

What is the difference between crypt abscess and cryptitis?

Answer 8

Cryptitis: neutrophil infiltrate into the epithelial lining of a crypt

Crypt abscess: neutrophil infiltrate into a crypt