Functional Histology of the Liver

Question 1

The surrounding capsule around the liver is called _______________.

Answer 1

Glisson’s capsule

Question 2

The hilum of the liver is called _____________.

Answer 2

the porta hepatis

Question 3

The hepatic portal vein carries about _______ percent of the blood to the liver.

Answer 3

75%

Question 4

The bile duct, as it enters the liver, is called the ___________.

Answer 4

hepatic duct

Question 5

True or false: the hepatic artery follows the hepatic vein in the liver.

Answer 5

False. The hepatic artery follows the hepatic portal vein. The hepatic portal vein drains blood across the hepatocytes to the hepatic veins, which carries the filtered product into the inferior vena cava.

Question 6

Which vessel in the liver has cuboidal lining?

Answer 6

The bile duct

Question 7

The lymphatic travels with what vessels?

Answer 7

Hepatic artery
Portal vein
Bile duct

Question 8

Plates of hepatocytes lead to the _____________.

Answer 8

central vein

Question 9

In cases of poisoning, the ____________ die first. In cases of ischemia, however, the ____________ die first.

Answer 9

cells near the hepatic triads; cells near the central vein

Question 10

Kupffer cells are _______________.

Answer 10

the macrophages of the liver

Question 11

Fenestrated endothelial cells are connected to hepatocytes across the ________________ by reticular fibers. Plasma is able to cross this space through the fenestrated endothelium. (RBCs are too big.)

Answer 11

space of Disse

Question 12

Ito cells, which lie between hepatocytes, store _______________.

Answer 12

lipid and vitamin A

Question 13

The portal triads are arranged hexagonally around _____________.

Answer 13

central veins

Question 14

Portal lobules are _________________.

Answer 14

triangular

Question 15

The portal lobule outlines the _________________.

Answer 15

flow of bile into bile ducts (since portal lobules cover the area around a portal triad)

Question 16

Toxic injury tends to affect the center of the ___________ lobule.

Answer 16

acinar (which outlines hepatic artery)

Question 17

True or false: the hepatocytes near the central veins typically make coagulation factors while the hepatocytes near the hepatic arteries make albumin.

Answer 17

False. All hepatocytes make the full complement of protein.

Question 18

The endothelial lining of the sinusoids is _____________ to allow plasma constituents to pass through.

Answer 18

fenestrated

Question 19

The space between the endothelium and the hepatocytes is called _____________.

Answer 19

the space of Disse (with collagenous fibers crossing)

Question 20

How much bile is produced daily?

Answer 20

500 mL

Question 21

Chemically, what does the liver do to double bonds?

Answer 21

It catalyzes an epoxide reaction that produces a hydroxyl group, which then gets conjugated.

Question 22

Ito cells lie between ________________ and contain ______________.

Answer 22

sinusoid hepatocytes; fat-soluble vitamins