Introduction to Infectious Disease: Diarrhea Flashcards

1
Q

What are the top two causes of death from infectious disease worldwide?

A

(1) Pneumonia

(2) Diarrhea

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2
Q

The non-inflammatory vs. inflammatory distinction overlaps perfectly with the ____________ distinction.

A

non-invasive vs. invasive

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3
Q

In terms of stool composition, how can you distinguish between inflammatory and non-inflammatory diarrhea.

A

Inflammatory: WBCs and RBCs

Non-inflammatory: watery

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4
Q

What pathogens are associated with non-inflammatory diarrhea?

A
Norwalk
Rotavirus
Giardia
Cholera
ETEC
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5
Q

What pathogens are associated with inflammatory diarrhea?

A
Campylobacter jejuni
Shigella
Salmonella
Escherichia coli O157:H7
Clostridium difficile
E. histolytica
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6
Q

The most common cause of traveler’s diarrhea is ______.

A

ETEC

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7
Q

Two things cause metabolic acidosis in cholera infection: ________________.

A

(1) poor tissue perfusion – causing lactic acid accumulation – and (2) excess bicarb excretion

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8
Q

The leading cause of diarrheal death worldwide is __________.

A

rotavirus; this happens less in the United States because of rotavirus vaccine

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9
Q

What virus normally causes diarrheal illness in older children and adults?

A

Norovirus

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10
Q

The most common symptoms of giardia infection?

A
Diarrhea
Fatigue
Abdominal pain
Bloating
Flatulence 
Malodorous stool
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11
Q

The most common cause of hemorrhagic diarrhea in the U.S. is _____________.

A

EHEC

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12
Q

The highest rates of EHEC are in ___________.

A

young children and the elderly

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13
Q

E. coli’s reservoir is __________.

A

the intestinal tracts of cattle

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14
Q

True or false: you need to immediately treat EHEC with bactrim.

A

False. Studies show that antibiotics can increase risk of toxin release. As such, just treat with fluids.

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15
Q

True or false: giardia responds to fluoroquinolones.

A

False.

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16
Q

What is the O in O157:H7? The H?

A
O = oligosaccharide
H = flagella
17
Q

Non-inflammatory, non-invasive diarrhea most often occurs in the ____________.

A

small intestine

18
Q

The incubation period for cholera is ______________.

A

18 hrs to 5 days

19
Q

Rotavirus preferentially affects the ______________.

A

infants and young children