Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

SS - Exam 3 > Skin Structure & Function > Flashcards

Skin Structure & Function Flashcards

1
Q

Bacterial dysbiosis

A

Allergic flare favoring opportunistic bacteria growth

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Lesion common in hyperadrenocosticism

A

Calcinosis cutis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Lesion common with pancreatic tumor

A

Feline paraneoplasic alopecia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Layers of skin effected by pemphigus foliaceus

A

Stratum granulosum and stratum spinosum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Layers of skin effected by cutaneous lupus erythematosus

A

Stratum basale and basement membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Stratum basale

A

Single row of cells resting on basement membrane
Constantly reproducing to replenish epi cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

stratum spinosum

A

Composed of daughter cells fo stratum basale
Appear connected by intercellular bridges =spines
Thicker at footpads, nasal planum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Stratum granulosum

A

Flattened cells, shrunk nuclei, contain keratohyalin granules**

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Composition of granules

A

Profilaggrins, loricrin, involucrin, caspase 14
Formation of SC, hydration of SC, filter UV radiation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Stratum corneum

A

Composed of terminally differentiated keratinocytes
Usually dead layer
Inhibit microbial adherence, limits growth/number

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Corneocytes

A

Surrounded by extracellular lipid (bricks and mortar)
Provide hydration, physical barrier

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Cornification

A

Active process that requires ATP to transform stratum basale into stratum corneum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Epidermal cell renewal time

A

Aka turnover rate
Time it takes for cells from basale cells to reach corneum. Dogs - 20-25d
Requires a delicate balance between cell death/renewal
Abnormal cornification - primary seborrhea of spaniels or zinc responsive dermatosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Desmosomes

A

Important for adhesion between keratinocytes
Help resist shearing forces
Ex pemphigus foliaceus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Adherence junction

A

Mediates adhesion between keratinocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Tight junction

A

Contributes to skin barrier function

17
Q

Gap junction

A

Intercellular routes of chemical communication

18
Q

Dermis is composed of

A

Fibers - collagen, elastin
Ground substance - proteoglycans, hyluronan
Cells - fibroblast, langerhans cells, mast cells
Epi appendages- sebaceous glands, hair follicles
Arrector pili muscles
Blood & lymph vessels
Nerves

19
Q

Sebaceous glands

A

Holocrine glands that open through a duct into the infundibulum
Secretes sebum over hair shaft/skin
Appearence, soft texture to hair/skin, permeability barrier, retain moisture

20
Q

Hair

A

Found only in mammals
Do not grow continuously but in cycles

21
Q

Simple hair follicle

A

One hair from one opening
Equine, bovine, procaine, ovien

22
Q

Compound hair follicles

A

Multiple hair follicles exit one hole
Canine, feline, ovine, caprine

23
Q

Hair growth cycle

A

Anagen - growing phase
Catagen - transition phase, signals end of active growth
Telogen - resting phase

24
Q

Function of hair

A

Physical barrier against trauma
UV protection
Thermoregulation/insulation
Repelling water
Sensation
Camouflage

25
Q

Specialized skin structure

A

Nasal planum
Foot pad
Claw

26
Q

Nasal planum

A

Color varies and can change overtime
Cobblestone textures
Shape and symmetry is important for function

27
Q

Diseases of nasal planum

A

Vitiligo
Discoid lupus erythematosus
Vasculitis

28
Q

Foot pad

A

Thick epidermis protect against mechanical trauma
Large fat deposits provide shock absorption
Abundant nerve supply
Abundant sweat glands

29
Q

Problems w foot pad

A

Hyperkerotitc and crusting
Ulcer
Sloughing

30
Q

Claw

A

Composed of hard/soft keratins
Growth rates influences by age, diet, environment, activity
Claw disorder as the only dermatological manifestation of diseases are rare - trauma lipoid onychondystrophy

31
Q

Functions of claws

A

Grasping, prehensile
Locomotion
Defensive and offensive apparatus

32
Q

Disorders of claws

A

Lupoid onychodystrophy
Onychocryptosis - ingrown claws

33
Q

SLO - canine symmetric lupoid onychondydrophy

A

Immune mediated disease that ONLY affects claws and nails
Biopsy of affected nail beds revealed histological features seen in cutaneous lupus erythematosus

34
Q

Signalment/CS of SLO

A

Young to middle aged dogs
Licking at paws, lameness, sloughing of claws
Can affect one or more claws, often involve more than one paw

35
Q

DX and TX of SLO

A

Clinical signs
Doxycycline + niacinamide
Oral modified cyclosporine
Fatty acid supplementation
Pain meds as needed

SS - Exam 3 (28 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions