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SS - Exam 3 > Disorders Of Anterior Uvea > Flashcards

Disorders Of Anterior Uvea Flashcards

1
Q

Iris anatomy

A

Posterior pigment epithelium
Stroma
Muscles - dilator, sphincter

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2
Q

Vascular tunic of the eye

A

Iris
Ciliary body
Choroid

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3
Q

Purpose of iris

A

Separating the anterior and posterior chamber
Controls amt of light entering eye
Color and pupil shape vary on species

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4
Q

Layers of pupil/eye

A

Ciliary zone
Collarette - not visible in all dogs, separate ciliary and pupillary zone
Central pupillary zone
Pupillary border

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5
Q

Largest potion of anterior uvea

A

Ciliary body
Pars plicata - anteriorly iris
Pars plana - posteriorly (retina)

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6
Q

Function of ciliary body

A

Aqueous humor production - ciliary process
^drainage - iridocorneal angle
Lens accommodation - Zonules (suspensory ligament of the lens)

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7
Q

Iris +ciliary body

A

Blood aqueous barrier
Posterior iris epithelium, iris vessels, nonpigmented ciliary body epithelium

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8
Q

Non inflammatory diseases

A

Heterochromia irides
Merle ocular dysgenesis
PPM
Iris hypoplasia
Iris coloboma
Uveal cysts
Iris atrophy
Iris nevus

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9
Q

Heterochromia irides

A

Different colors within one iris or between two irides
Sole manifestation of ocular color dilution in breeds
Can be component of ocular merling - accompanied by multiple ocular anomalies

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10
Q

Merle ocular dysgenesis

A

Microphthalmia
Dyscoria (shape)
Corectopia (off center)
Iris hypoplasia
Heterochromia irides
Cataract
Staphylomas
Retinal detachments
PPM

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11
Q

Breeds/significance of Merle ocular dysgenesis

A

Australian shepherds, Great Danes, collies, dachshunds
Severity of lesions correlates with amt of white in coat /fur
Aussies - autosomal recessive inheritance

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12
Q

PPM

A

Persistent pupillary membranes
Remnants of BV (supply during development) remain
Normal strands are gone 6 weeks postpartum
Common in basenji, corgi, mastiff, chow

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13
Q

Location of PPM

A

Iris to Iris
Iris to lens (cataract)
Iris to cornea (corneal opacities)

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14
Q

Iris hypoplasia

A

Thinning of iris tissue
Partial or full defects
- muscles - prevent pupil from constricting/dilating
Can be seen alone or with other anomalies

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15
Q

Iris coloboma

A

Lack of iris tissue
Typical @6 o’clock vs atypical (any other location)
Can present by itself or with others like lens, optic nerve, retinal colobomas

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16
Q

uveal cysts

A

Common in dogs
Posterior iris epithelium and inner ciliary body epithelium are common locations
Breeds - Boston’s, retrievers - GRU

17
Q

Iris atrophy (senile)

A

Age related thinning of iris tissue - iris stroma, pupillary margin will eventually prevent movement
Animals may exhibit sensitivity to /squinting in light

18
Q

Iris nevus

A

Proliferation of melanocytes - well demarcated, flat or slightly elevated
Usually not progressive but have potential to undergo malignant trans formation- cats
Can be challenging to differentiate from melanoma

19
Q

Neoplastic diseases

A

Melanocytic neoplasia
Uveal melanoma - dog and cat, horse
Iridociliary epithelial neoplasia
Metastatic neoplasia

20
Q

Melanocytic neoplasia

A

Most common primary intraocular neoplasia
Melanocytoma - benign
Melanoma = malignant
Raised mass/lesion og from iris or CB
Pigmented = uveal cyst
Non pig = amelanotic melanoma

21
Q

Uveal melanoma - dog

A

Typically benign
Locally invasive - secondary uveitis /glaucoma
Retrievers and GS

22
Q

Uveal melanoma - cats

A

Feline diffuse iris melanoma (FDIM)
Malignant - raised, pigmented, can interfere with pupillary movement and secondary glaucoma

Can metastasize to liver/lungs

23
Q

Uveal melanoma - horse

A

Typically benign
Locally invasive, can lead to uveitis & secondary glaucoma
Common in older horses/Arabians

24
Q

Treating Melanocytic neoplasia

A

Diode laser therapy
Iridectomy
Enucleation

25
Q

Addition Melanocytic treatment for cats

A

Thoracic radiographs
Abdominal ultrasound
FNA lymph nodes

26
Q

Iridiociliary epithelial neoplasia

A

Ciliary body adenoma - common
Pink, vascular mass - usually visible behind pupil
Middle aged to older animals
Locally aggressive - TX is enucleation in most cases

27
Q

Metastatic neoplasia

A

Lymphoma - most common
Can present as subtle uveitis or mass lesions
Poor long term prognosis for eye or patient
-if presents in eye, its likely the cancer is in other parts of the body

SS - Exam 3 (28 decks)

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