Skin pathology: Inflammatory dermatoses Flashcards
function of skin
barrier against environmental insults and fluid loss
what composes the skin
epidermis and dermis
Epidermis has what in it, and what are the layers
keratinocytes
- statum basalis
- stratum spinosum
- stratum granulosum
- statum corneum
characterize Stratum basalis
regenerative (stem cell) layer
characterize Stratum spinosum
desmosomes between keratinocytes
characterize Stratum granulosum
granules in keratinocytes
characterize Stratum corneum
keratin in anucleate cells
what is located in the dermis
connective tissue
nerve endings
blood and lymphatic vessels
adnexal structures
what are adnexal structures
hair shafts
sweat glands
sebaceous glands
What is atopic (eczematous dermatitis)
pruritic, erythematous, oozing rash with vesicles and edema
where does atopic (eczematous) dermatitis usually occur
face and flexor surfaces
what type of hypersensitivity is atopic (eczematous) dermatitis
Type I hypersensitivity
what is atopic (eczematous) dermatitis associated with
asthma
allergic rhinitis
what is conact dermatitis
pruritic, erythematous, oozing rash with vesicles and edema
what can cause contact dermatitis
exposure to allergens:
- Poison Ivy and Nickel Jewelry ( type IV)
- irritant chemicals (e.g., detergents)
- drugs (e.g., penicillin)
how is contact dermatitis treated
- removal of offending agent
- topical glucocorticoids, if needed
what is acne vulgaris
- comedones (whiteheads and blackheads)
- pustules ( pimples)
- nodules