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Skin histology & spotter qs Flashcards

1
Q

Which skin pathology is depicted in this slide? [1]

A

Pemphigus valguris:
* pemphigus shows linear/granular deposition of immunoglobulins (Igs) and C3 in the epidermal ICS

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2
Q

What is this skin pathology depicted? [1]

A

pemphigus vulgaris show suprabasal epidermal acantholysis

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3
Q

What is this skin pathology? [1]

A

Leukocytoclastic Vasculitis

Fibrin deposition can be identified within the vessel wall

The perivascular inflammatory infiltrate is comprised predominantly of neutrophils but eosinophils are also present.

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4
Q

What is this skin pathology? [1]

A

Leukocytoclastic Vasculitis:

Fibrin deposition involving the wall of the dermal vessels entirely associated with leukocytoclasis

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5
Q

What is the underlying cause of this inflammation? [1]

A

Sarcoid Granuloma

Sarcoid lymph node

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6
Q

What skin pathology is depicted? [1]

What is the most likey pathogen causing this? [1]

A

Folliculitis: Staphylococcus aureus

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7
Q

What is this skin pathology depicted? [1]

A

Folliculitis

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8
Q

What is this skin pathology depicted? [1]

A

Cellulitis: Infection of the dermis and subcutaneous fat

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9
Q

What skin pathology is this? [1]

A

HPV (viral warts / verucca)

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10
Q

What skin pathology is depicted? [1]

A

HPV (viral warts / verucca)

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11
Q

What skin pathology is depicted? [1]

A

HPV (viral warts / verucca)

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12
Q

What skin pathology is depicted? [1]

A

Molluscum contagiosum: water warts

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13
Q

What skin pathology is depicted? [1]

A

Molluscum contagiosum

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14
Q

What is the skin pathology depicted? [1]

A

Molluscum contagiosum

It is a viral skin infection caused by a large DNA pox virus with an incubation period of 2 to 7 weeks. The lesions consist of multiple pearly round papules measuring 3 to 5 mm in size with central umbilication.

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15
Q

What is the skin pathology depicted? [1]

A

Molluscum contagiosum

There is lobular hyperplasia of epidermis into the dermis resulting in a cup-shaped lesion. The basal layers appear normal, but the keratinocytes of stratum malpighii become enlarged and acquire eosinophilic inclusion bodies - Henderson-Patterson bodies that contain virus particles.

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16
Q

What skin pathology is depicted? [1]

A

Pityriasis versicolour; Pityrosporum orbiculare

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17
Q

What is this skin pathology depicted? [1]

A

Pityriasis versicolour

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18
Q

What are the arrows pointing at here? [2]

A

Scabies

Shave skin biopsy showing hyperkeratosis and mild epidermal spongiosis. There are numerous mites, eggs and egg shells within the stratum corneum. There is a mild superficial lymphocytic infiltrate in the papillary dermis (20x).

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19
Q

What skin pathology is depicted here? [1]

What layer of the skin is depicted?

A

Scabies

Higher power image of multiple mites within the stratum corneum in a shave biopsy specimen of crusted scabies (40x).

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20
Q

What skin pathology is depicted here? [1]

A

Scabies

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21
Q

What skin pathology is depicted? [1]

A

Scabies

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22
Q

What pathogen is causing this pathology? [1]

A

Tuberculosis

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23
Q

What pathogen is causing this slide? [1]

A

Mycobacterium leprae or mycobacterium lepromatosis

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24
Q

What pathogen is causing this slide? [1]

A

Mycobacterium leprae or mycobacterium lepromatosis

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25
This cells is capable of
**Mast cell-mediated inflammation** Antibody-mediated inflammation Immune complex mediated inflammation Delayed hypersensitivity Automimmunity
26
This animal is would cause which response? Mast cell-mediated inflammation Antibody-mediated inflammation Immune complex mediated inflammation Delayed hypersensitivity Automimmunity
**Mast cell-mediated inflammation** Dermatophagoides pteronyssinus: **Der P1** is an enzyme allergen from the faecal pellets of the dust mite.
27
This symptoms is a result of Mast cell-mediated inflammation Antibody-mediated inflammation Immune complex mediated inflammation Delayed hypersensitivity Automimmunity
**Mast cell-mediated inflammation** Urticaria: IgE mediated pathway Mast cell reactivity is increased in active urticaria by local inflammatory cytokines and neuropeptides.
28
These symptoms are a consequence of: Mast cell-mediated inflammation Antibody-mediated inflammation Immune complex mediated inflammation Delayed hypersensitivity Automimmunity
**Mast cell-mediated inflammation** Acute angioedema
29
Pemphigus Vulgaris is a result of Mast cell-mediated inflammation Antibody-mediated inflammation Immune complex mediated inflammation Delayed hypersensitivity Automimmunity
**Antibody-mediated inflammation**
30
This symptom is a result of? Mast cell-mediated inflammation Antibody-mediated inflammation Immune complex mediated inflammation Delayed hypersensitivity Automimmunity
**Antibody-mediated inflammation** | Pemphigus Vulgaris
31
This histological staining is a result of Mast cell-mediated inflammation Antibody-mediated inflammation Immune complex mediated inflammation Delayed hypersensitivity Automimmunity
**Antibody-mediated inflammation** | Pemphigus Vulgaris
32
This rash is a result of Mast cell-mediated inflammation Antibody-mediated inflammation Immune complex mediated inflammation Delayed hypersensitivity Automimmunity
I**mmune complex mediated inflammation** | SLE
33
This flower would cause Mast cell-mediated inflammation Antibody-mediated inflammation Immune complex mediated inflammation Delayed hypersensitivity Automimmunity
**Delayed hypersensitivity**
34
This symptom is a result of Mast cell-mediated inflammation Antibody-mediated inflammation Immune complex mediated inflammation Delayed hypersensitivity Autoimmunity
**Autoimmunity** | Alopecia Areata (AA)
35
This symptom is a result of Mast cell-mediated inflammation Antibody-mediated inflammation Immune complex mediated inflammation Delayed hypersensitivity Autoimmunity
**Autoimmunity** | Vitiligo
36
This is Vitiligo Erysipelas Pityriasis versicolour Hansen disease Lupus Vulgaris-
**Vitiligo**
37
This patient is suffering from Vitiligo Erysipelas Pityriasis versicolour Hansen disease Lupus Vulgaris
**Lupus Vulgaris**: cutaneous TB
38
This patient is suffering from Vitiligo Erysipelas Pityriasis versicolour Hansen disease Lupus Vulgaris
**Lupus Vulgaris**: cutaneous TB
39
This patient is suffering from Vitiligo Erysipelas Pityriasis versicolour Hansen disease Lupus Vulgaris
**Erysipelas**: (cellulitis of the face) but just in the dermis and not in subcutaneous fat
40
This patient is suffering from Vitiligo Erysipelas Pityriasis versicolour Hansen disease Lupus Vulgaris
**Erysipelas**
41
This patient is suffering from Cellulitis Erysipelas Pityriasis versicolour Hansen disease Lupus Vulgaris
**Cellulitis**: Infection of the dermis and subcutaneous fat
42
This patient is suffering from Cellulitis Erysipelas Pityriasis versicolour Hansen disease Lupus Vulgaris
**Cellulitis**
43
Cellulitis Erysipelas Pityriasis versicolour Hansen disease Lupus Vulgaris
**Pityriasis versicolour**
44
Cellulitis Vitiligo Pityriasis versicolour Hansen disease Lupus Vulgaris
**Pityriasis versicolour**
45
Vitiligo vs Pityriasis versicolour? [3]
**vitiligo** * often develops **symmetrically** * **normal texture** * anywhere (including face) **pityriasis versicolor** * less symmetrical skin * slightly scaly or flaky.les * neck, back, chest, upper arms, and stomach
46
Cellulitis Vitiligo Pityriasis versicolour Hansen disease Lupus Vulgaris
**Hansen disease**: Lupus : Mycobacterium leprae or mycobacterium lepromatosis
47
Leprosy Leishmania (leishmaniasis) Lyme disease Scabies Ringworm
**Leprosy**
48
Leprosy Leishmania (leishmaniasis) Lyme disease Scabies Ringworm
**Leprosy**
49
Leprosy Leishmania (leishmaniasis) Lyme disease Scabies Ringworm
**Ringworm**
50
Leprosy Leishmania (leishmaniasis) Lyme disease Scabies Ringworm
**Ringworm**
51
Leprosy Leishmania (leishmaniasis) Lyme disease Scabies Ringworm
**Scabies**
52
Leprosy Leishmania (leishmaniasis) Lyme disease Scabies Ringworm
**Scabies** (Crusted)
53
Leprosy Leishmania (leishmaniasis) Lyme disease Scabies Ringworm
**Lyme disease**
54
Leprosy Leishmania (leishmaniasis) Lyme disease Scabies Ringworm
Lyme disease
55
What is the pathogen causing this disease? [1] What is the name for this presentation? p1[
**Scrofuloderma** follows the direct invasion of the skin from **tuberculosis** in an underlying lymph node or bone, often in association with pulmonary TB.
56
Name the cause of this symptom [1]
**Candida albicans**
57
Name the causative agent of this symptom [1]
**Candida albicans**
58
Molluscum contagiosum Herpes Zoster Human papillomavirus Cellulitis Impetigo Folliculitis
**Molluscum contagiosum**
59
Molluscum contagiosum Herpes Zoster Human papillomavirus Cellulitis Impetigo Folliculitis
**Molluscum contagiosum**
60
Molluscum contagiosum Herpes Zoster Human papillomavirus Cellulitis Impetigo Folliculitis
**Molluscum contagiosum**
61
Molluscum contagiosum Herpes Zoster Human papillomavirus Cellulitis Impetigo Folliculitis
**Herpes Zoster**
62
Molluscum contagiosum Herpes Zoster Human papillomavirus Cellulitis Impetigo Folliculitis
**Herpes Zoster**
63
Molluscum contagiosum Herpes Virus Human papillomavirus Cellulitis Impetigo Folliculitis
**Herpes Virus**
64
Molluscum contagiosum Herpes Virus Herpes Zoster Cellulitis Impetigo Folliculitis
**Herpes Zoster**: reactivation of varicella zoster virus
65
Molluscum contagiosum Herpes Virus Herpes Zoster Cellulitis Impetigo Folliculitis
**Folliculitis**
66
Molluscum contagiosum Herpes Virus Herpes Zoster Cellulitis Impetigo Folliculitis
**Folliculitis**
67
Molluscum contagiosum Herpes Virus Herpes Zoster Cellulitis Impetigo Folliculitis
**Folliculitis**
68
Molluscum contagiosum Herpes Virus Herpes Zoster Cellulitis Impetigo Folliculitis
**Impetigo**
69
Molluscum contagiosum Herpes Virus Herpes Zoster Cellulitis Impetigo Folliculitis
**Impetigo**
70
Molluscum contagiosum Herpes Virus Herpes Zoster Cellulitis Impetigo Folliculitis
**Impetigo**
71
Scalded skin syndrome Necrotising fasciitis Pemphigus Vulgaris Leukocytoclastic Vasculitis Neisseria meningitidis
**Leukocytoclastic Vasculitis**
72
Scalded skin syndrome Necrotising fasciitis Pemphigus Vulgaris Leukocytoclastic Vasculitis Neisseria meningitidis
**Leukocytoclastic Vasculitis**
73
Scalded skin syndrome Necrotising fasciitis Pemphigus Vulgaris Leukocytoclastic Vasculitis Neisseria meningitidis
**Neisseria meningitidis**
74
Scalded skin syndrome Necrotising fasciitis Pemphigus Vulgaris Leukocytoclastic Vasculitis Neisseria meningitidis
**Neisseria meningitidis**
75
Scalded skin syndrome Necrotising fasciitis Pemphigus Vulgaris Leukocytoclastic Vasculitis Neisseria meningitidis
**Scalded skin syndrome**
76
Scalded skin syndrome Necrotising fasciitis Pemphigus Vulgaris Leukocytoclastic Vasculitis Neisseria meningitidis
**Scalded skin syndrome**
77
Scalded skin syndrome Necrotising fasciitis Pemphigus Vulgaris Leukocytoclastic Vasculitis Neisseria meningitidis
**Scalded skin syndrome**
78
Scalded skin syndrome Necrotising fasciitis Pemphigus Vulgaris Leukocytoclastic Vasculitis Neisseria meningitidis
**Necrotising fasciitis**
79
Scalded skin syndrome Necrotising fasciitis Pemphigus Vulgaris Leukocytoclastic Vasculitis Neisseria meningitidis
**Necrotising fasciitis**

LOCO2 (58 decks)

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