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LOCO2 > Skin histology & spotter qs > Flashcards

Skin histology & spotter qs Flashcards

1
Q

Which skin pathology is depicted in this slide? [1]

A

Pemphigus valguris:
* pemphigus shows linear/granular deposition of immunoglobulins (Igs) and C3 in the epidermal ICS

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2
Q

What is this skin pathology depicted? [1]

A

pemphigus vulgaris show suprabasal epidermal acantholysis

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3
Q

What is this skin pathology? [1]

A

Leukocytoclastic Vasculitis

Fibrin deposition can be identified within the vessel wall

The perivascular inflammatory infiltrate is comprised predominantly of neutrophils but eosinophils are also present.

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4
Q

What is this skin pathology? [1]

A

Leukocytoclastic Vasculitis:

Fibrin deposition involving the wall of the dermal vessels entirely associated with leukocytoclasis

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5
Q

What is the underlying cause of this inflammation? [1]

A

Sarcoid Granuloma

Sarcoid lymph node

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6
Q

What skin pathology is depicted? [1]

What is the most likey pathogen causing this? [1]

A

Folliculitis: Staphylococcus aureus

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7
Q

What is this skin pathology depicted? [1]

A

Folliculitis

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8
Q

What is this skin pathology depicted? [1]

A

Cellulitis: Infection of the dermis and subcutaneous fat

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9
Q

What skin pathology is this? [1]

A

HPV (viral warts / verucca)

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10
Q

What skin pathology is depicted? [1]

A

HPV (viral warts / verucca)

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11
Q

What skin pathology is depicted? [1]

A

HPV (viral warts / verucca)

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12
Q

What skin pathology is depicted? [1]

A

Molluscum contagiosum: water warts

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13
Q

What skin pathology is depicted? [1]

A

Molluscum contagiosum

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14
Q

What is the skin pathology depicted? [1]

A

Molluscum contagiosum

It is a viral skin infection caused by a large DNA pox virus with an incubation period of 2 to 7 weeks. The lesions consist of multiple pearly round papules measuring 3 to 5 mm in size with central umbilication.

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15
Q

What is the skin pathology depicted? [1]

A

Molluscum contagiosum

There is lobular hyperplasia of epidermis into the dermis resulting in a cup-shaped lesion. The basal layers appear normal, but the keratinocytes of stratum malpighii become enlarged and acquire eosinophilic inclusion bodies - Henderson-Patterson bodies that contain virus particles.

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16
Q

What skin pathology is depicted? [1]

A

Pityriasis versicolour; Pityrosporum orbiculare

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17
Q

What is this skin pathology depicted? [1]

A

Pityriasis versicolour

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18
Q

What are the arrows pointing at here? [2]

A

Scabies

Shave skin biopsy showing hyperkeratosis and mild epidermal spongiosis. There are numerous mites, eggs and egg shells within the stratum corneum. There is a mild superficial lymphocytic infiltrate in the papillary dermis (20x).

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19
Q

What skin pathology is depicted here? [1]

What layer of the skin is depicted?

A

Scabies

Higher power image of multiple mites within the stratum corneum in a shave biopsy specimen of crusted scabies (40x).

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20
Q

What skin pathology is depicted here? [1]

A

Scabies

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21
Q

What skin pathology is depicted? [1]

A

Scabies

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22
Q

What pathogen is causing this pathology? [1]

A

Tuberculosis

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23
Q

What pathogen is causing this slide? [1]

A

Mycobacterium leprae or mycobacterium lepromatosis

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24
Q

What pathogen is causing this slide? [1]

A

Mycobacterium leprae or mycobacterium lepromatosis

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25
Q

This cells is capable of

A

Mast cell-mediated inflammation
Antibody-mediated inflammation
Immune complex mediated inflammation
Delayed hypersensitivity
Automimmunity

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26
Q

This animal is would cause which response?

Mast cell-mediated inflammation
Antibody-mediated inflammation
Immune complex mediated inflammation
Delayed hypersensitivity
Automimmunity

A

Mast cell-mediated inflammation

Dermatophagoides pteronyssinus: Der P1 is an enzyme allergen from the faecal pellets
of the dust mite.

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27
Q

This symptoms is a result of

Mast cell-mediated inflammation
Antibody-mediated inflammation
Immune complex mediated inflammation
Delayed hypersensitivity
Automimmunity

A

Mast cell-mediated inflammation

Urticaria: IgE mediated pathway

Mast cell reactivity is increased in active urticaria by local inflammatory cytokines and neuropeptides.

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28
Q

These symptoms are a consequence of:

Mast cell-mediated inflammation
Antibody-mediated inflammation
Immune complex mediated inflammation
Delayed hypersensitivity
Automimmunity

A

Mast cell-mediated inflammation

Acute angioedema

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29
Q

Pemphigus Vulgaris is a result of

Mast cell-mediated inflammation
Antibody-mediated inflammation
Immune complex mediated inflammation
Delayed hypersensitivity
Automimmunity

A

Antibody-mediated inflammation

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30
Q

This symptom is a result of?

Mast cell-mediated inflammation
Antibody-mediated inflammation
Immune complex mediated inflammation
Delayed hypersensitivity
Automimmunity

A

Antibody-mediated inflammation

Pemphigus Vulgaris

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31
Q

This histological staining is a result of

Mast cell-mediated inflammation
Antibody-mediated inflammation
Immune complex mediated inflammation
Delayed hypersensitivity
Automimmunity

A

Antibody-mediated inflammation

Pemphigus Vulgaris

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32
Q

This rash is a result of

Mast cell-mediated inflammation
Antibody-mediated inflammation
Immune complex mediated inflammation
Delayed hypersensitivity
Automimmunity

A

Immune complex mediated inflammation

SLE

33
Q

This flower would cause

Mast cell-mediated inflammation
Antibody-mediated inflammation
Immune complex mediated inflammation
Delayed hypersensitivity
Automimmunity

A

Delayed hypersensitivity

34
Q

This symptom is a result of

Mast cell-mediated inflammation
Antibody-mediated inflammation
Immune complex mediated inflammation
Delayed hypersensitivity
Autoimmunity

A

Autoimmunity

Alopecia Areata (AA)

35
Q

This symptom is a result of

Mast cell-mediated inflammation
Antibody-mediated inflammation
Immune complex mediated inflammation
Delayed hypersensitivity
Autoimmunity

A

Autoimmunity

Vitiligo

36
Q

This is

Vitiligo
Erysipelas
Pityriasis versicolour
Hansen disease
Lupus Vulgaris-

A

Vitiligo

37
Q

This patient is suffering from

Vitiligo
Erysipelas
Pityriasis versicolour
Hansen disease
Lupus Vulgaris

A

Lupus Vulgaris: cutaneous TB

38
Q

This patient is suffering from

Vitiligo
Erysipelas
Pityriasis versicolour
Hansen disease
Lupus Vulgaris

A

Lupus Vulgaris: cutaneous TB

39
Q

This patient is suffering from

Vitiligo
Erysipelas
Pityriasis versicolour
Hansen disease
Lupus Vulgaris

A

Erysipelas: (cellulitis of the face) but just in the dermis and not in subcutaneous fat

40
Q

This patient is suffering from

Vitiligo
Erysipelas
Pityriasis versicolour
Hansen disease
Lupus Vulgaris

A

Erysipelas

41
Q

This patient is suffering from

Cellulitis
Erysipelas
Pityriasis versicolour
Hansen disease
Lupus Vulgaris

A

Cellulitis: Infection of the dermis and subcutaneous fat

42
Q

This patient is suffering from

Cellulitis
Erysipelas
Pityriasis versicolour
Hansen disease
Lupus Vulgaris

A

Cellulitis

43
Q

Cellulitis
Erysipelas
Pityriasis versicolour
Hansen disease
Lupus Vulgaris

A

Pityriasis versicolour

44
Q

Cellulitis
Vitiligo
Pityriasis versicolour
Hansen disease
Lupus Vulgaris

A

Pityriasis versicolour

45
Q

Vitiligo vs Pityriasis versicolour? [3]

A

vitiligo
* often develops symmetrically
* normal texture
* anywhere (including face)

pityriasis versicolor
* less symmetrical skin
* slightly scaly or flaky.les
* neck, back, chest, upper arms, and stomach

46
Q

Cellulitis
Vitiligo
Pityriasis versicolour
Hansen disease
Lupus Vulgaris

A

Hansen disease: Lupus : Mycobacterium leprae or mycobacterium lepromatosis

47
Q

Leprosy
Leishmania (leishmaniasis)
Lyme disease
Scabies
Ringworm

A

Leprosy

48
Q

Leprosy
Leishmania (leishmaniasis)
Lyme disease
Scabies
Ringworm

A

Leprosy

49
Q

Leprosy
Leishmania (leishmaniasis)
Lyme disease
Scabies
Ringworm

A

Ringworm

50
Q

Leprosy
Leishmania (leishmaniasis)
Lyme disease
Scabies
Ringworm

A

Ringworm

51
Q

Leprosy
Leishmania (leishmaniasis)
Lyme disease
Scabies
Ringworm

A

Scabies

52
Q

Leprosy
Leishmania (leishmaniasis)
Lyme disease
Scabies
Ringworm

A

Scabies (Crusted)

53
Q

Leprosy
Leishmania (leishmaniasis)
Lyme disease
Scabies
Ringworm

A

Lyme disease

54
Q

Leprosy
Leishmania (leishmaniasis)
Lyme disease
Scabies
Ringworm

A

Lyme disease

55
Q

What is the pathogen causing this disease? [1]

What is the name for this presentation? p1[

A

Scrofuloderma follows the direct invasion of the skin from tuberculosis in an underlying lymph node or bone, often in association with pulmonary TB.

56
Q

Name the cause of this symptom [1]

A

Candida albicans

57
Q

Name the causative agent of this symptom [1]

A

Candida albicans

58
Q

Molluscum contagiosum
Herpes Zoster
Human papillomavirus
Cellulitis
Impetigo
Folliculitis

A

Molluscum contagiosum

59
Q

Molluscum contagiosum
Herpes Zoster
Human papillomavirus
Cellulitis
Impetigo
Folliculitis

A

Molluscum contagiosum

60
Q

Molluscum contagiosum
Herpes Zoster
Human papillomavirus
Cellulitis
Impetigo
Folliculitis

A

Molluscum contagiosum

61
Q

Molluscum contagiosum
Herpes Zoster
Human papillomavirus
Cellulitis
Impetigo
Folliculitis

A

Herpes Zoster

62
Q

Molluscum contagiosum
Herpes Zoster
Human papillomavirus
Cellulitis
Impetigo
Folliculitis

A

Herpes Zoster

63
Q

Molluscum contagiosum
Herpes Virus
Human papillomavirus
Cellulitis
Impetigo
Folliculitis

A

Herpes Virus

64
Q

Molluscum contagiosum
Herpes Virus
Herpes Zoster
Cellulitis
Impetigo
Folliculitis

A

Herpes Zoster: reactivation of varicella zoster virus

65
Q

Molluscum contagiosum
Herpes Virus
Herpes Zoster
Cellulitis
Impetigo
Folliculitis

A

Folliculitis

66
Q

Molluscum contagiosum
Herpes Virus
Herpes Zoster
Cellulitis
Impetigo
Folliculitis

A

Folliculitis

67
Q

Molluscum contagiosum
Herpes Virus
Herpes Zoster
Cellulitis
Impetigo
Folliculitis

A

Folliculitis

68
Q

Molluscum contagiosum
Herpes Virus
Herpes Zoster
Cellulitis
Impetigo
Folliculitis

A

Impetigo

69
Q

Molluscum contagiosum
Herpes Virus
Herpes Zoster
Cellulitis
Impetigo
Folliculitis

A

Impetigo

70
Q

Molluscum contagiosum
Herpes Virus
Herpes Zoster
Cellulitis
Impetigo
Folliculitis

A

Impetigo

71
Q

Scalded skin syndrome
Necrotising fasciitis
Pemphigus Vulgaris
Leukocytoclastic Vasculitis
Neisseria meningitidis

A

Leukocytoclastic Vasculitis

72
Q

Scalded skin syndrome
Necrotising fasciitis
Pemphigus Vulgaris
Leukocytoclastic Vasculitis
Neisseria meningitidis

A

Leukocytoclastic Vasculitis

73
Q

Scalded skin syndrome
Necrotising fasciitis
Pemphigus Vulgaris
Leukocytoclastic Vasculitis
Neisseria meningitidis

A

Neisseria meningitidis

74
Q

Scalded skin syndrome
Necrotising fasciitis
Pemphigus Vulgaris
Leukocytoclastic Vasculitis
Neisseria meningitidis

A

Neisseria meningitidis

75
Q

Scalded skin syndrome
Necrotising fasciitis
Pemphigus Vulgaris
Leukocytoclastic Vasculitis
Neisseria meningitidis

A

Scalded skin syndrome

76
Q

Scalded skin syndrome
Necrotising fasciitis
Pemphigus Vulgaris
Leukocytoclastic Vasculitis
Neisseria meningitidis

A

Scalded skin syndrome

77
Q

Scalded skin syndrome
Necrotising fasciitis
Pemphigus Vulgaris
Leukocytoclastic Vasculitis
Neisseria meningitidis

A

Scalded skin syndrome

78
Q

Scalded skin syndrome
Necrotising fasciitis
Pemphigus Vulgaris
Leukocytoclastic Vasculitis
Neisseria meningitidis

A

Necrotising fasciitis

79
Q

Scalded skin syndrome
Necrotising fasciitis
Pemphigus Vulgaris
Leukocytoclastic Vasculitis
Neisseria meningitidis

A

Necrotising fasciitis

LOCO2 (58 decks)

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