Inflammatory joint conditions (RA) Flashcards

1
Q

State 5 yellow flags for pain [5]

A

History of numerous episodes
Duration of symptoms
Intensity of symptoms
Anxiety / depression
Loss of control
Catastrophizing

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2
Q

Muscoloskeletal pain can normally be triaged into which three categories? [3]

A

Back pain
Myalgia: muscle pain
Arthralgia: joint pain

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3
Q

What are the sources of MSK pain? [4]

A

Soft tissue
Bone
Joint
Referred / central pain

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4
Q

State three categories of inflammatory joint disease [3]

A
  1. Infection: septic arthiritis or generalised arthralgia
  2. crystal arthropathy: gout and pseudogout
  3. Autoimmune disorders: RA, spondarthritis, connective tissue disease
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5
Q

When taking a MSK history what would you ask? [4]

A

History
- Episodic and / or joints additive?
- mono, oligo or poly joints?
- symmetrical?

Precipitating factors (infection, trauma, drugs)?

Responsiveness to therapy?

Systemic illness?

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6
Q

Many joints / polyarthralgia would be suggestive of what type of disease? [1]

Single joint / monarthralgia would be suggestive of what type of disease? [1]

A

polyarthralgia: autoimmune disorders

monarthralgia: inflammatory disorder

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7
Q

Why do you ask if joint / bone pain (e.g. polyarticular pain) has been around for 6 weeks? [1]

A

Viral arthritis is a cause of joint pain: if 6 weeks probably something else like RA

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8
Q

Draw a flow chart for diagnosis of joint pain

A
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9
Q

Describe the features of RA [3]

A

Symmetrical

Hands and feet in 80% of cases

Early morning stiffness

Valgus deformity

Bakers cyst: synovial fluid at popliteal area

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10
Q

What is this sign of RA [1]

A

Bakers cyst: synovial fluid at popliteal area

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11
Q

State three eye complications of RA [3]

Why is the eye commonly a problem? [1]

A

RA effects type 2 collagen; get lots of type 2 collagen in they eye

Keratoconjunctivitis sicca

Scleritis & episcleritis

Scleromalacia perforans: intraocular contents prolaspes out of the sclera

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12
Q

Describe three neuromuscular complications of RA [3]

A

Muscle wasting
Carpal tunnel syndrome
Atlanto-axial subluxation: odointal peg impinges on the spinal cord

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13
Q

What causes cervical myelopathy in RA patients? [1]

What are signs of cervical myelopathy? [5]

A

Compression of the spinal cord and brain stem is typically caused by atlantoaxial instability (AAI) or atlantoaxial subluxation (AAS)

spasticity (sustained muscle contractions)
hyperreflexia
pathologic reflexes
digit/hand clumsiness
gait disturbance

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14
Q

State a cardiac [1] and bone [1] complication of RA

A

ischaemic heart disease

osteoporosis

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15
Q

What are characteristics of RA in imaging? [3]

A

bone erosions
soft tissue swelling
periarticular osteoporosis

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16
Q

Early detection of RA synovitis using ultrasound would identify what? [3]

A

Synovial thickening

Effusion

Power doppler signal

17
Q

State the classification criteria for RA [6]

A

Morning stiffness

Arthritis of three or more joint areas

Symmetric arthritis

Rheumatoid factor

Rheumatoid nodules

Characteristic radiological changes

18
Q

State three connective tissue diseases

A

Systemic lupus erythematosus:

Scleroderma / Systemic sclerosis: progressive atrophy of soft tissue

Dermatomyositis: high level of creatine kinase; muscle weakness - get lots of rashes. proximal weakness

19
Q

Describe pathophysiology of Systemic lupus erythematosus

A

Characterised by anti nuclear antibodies (antibodies to proteins within the persons own nucleus): causes immune system to target these proteins and generates inflammatory response / loss of tolerance

Inflammation leads to the symptoms

20
Q

Describe the symptoms of SLE

A

90% of patients have arthritis:
* symmetrical small joint polyarticular arthiritis (most common)
* jaccoud arthropathy (rare)
* avascular necrosis

Fatigue
Weight loss
arthralgia
myalgia
fever
butterfly rash: gets worse with sunlight
shortness of breath
hair loss