skeletal system Flashcards
what are the 5 functions of the skeletal system
structural support protection of internal organs provides leverage for movement stores calcium produces blood cells
bone is a specialised form of what
connective tissue
cells are suspended in a matrix but what hardens the matrix
mineral salts
what is the name of the organic component found in bone
osteoid (collagen and protein)
strong and flexible
what is the name of the inorganic component of bone
Hydroxyapatite (calcium phosphate and calcium carbonate)
hard and relatively inflexible, brittle
what makes bones strong but flexible
combination of organic and inorganic compounds
how many types of bone cell are there
4
what do osteoblasts do
produce new bone
secrete osteoid (organic compound)
responsible for mineral deposition
what do osteocytes do
mature bone cells
located within lacunae (nests) within the bone
maintain the matrix (ensure well nourished)
what do osteoclasts do
remove mineral from the matrix
responsible for bone remodelling (break down bone a bit like phagocytes and free up mineral to use for plasma)
what do osteogenic stem cells do
found in periostem and endosteum. develop into osteoblasts (new bone)
what are the 2 types of bone tissue
compact bone (surface of bone) cancellous (spongy interior)
what is the name of the functional unit of compact bone
osteon (Haversian system) consists of haversian canal with artery running through it
are osteons aligned in the same or opposite direction
same to give the bone strength
what is callous bone made up of and how are they arranged
trabeculae - arranged haphazardly
what is in between trabeculae
bone marrow
draw and label long bone
draw it
what are the 2 types of bone marrow
red bone marrow (myeloid tissue - haemopoietic produces blood cells)
yellow bone marrow (fatty tissue that can onlybe stimulated to produce blood cells again in severe anaemia)
which age group has increased bone marrow
children as needed to grow as well as replace
what are the 4 shapes of bone and give an example of each
long (femur)
short (carpals)
flat (sternum)
irregular (vertebrae)
draw flat bone
draw it - NOT PRINTED!
what is the difference between intramembranous ossification and endochondral ossification
intramembranous ossification (no cartilage phase - flat bones and clavicles) endochondral ossification (cartilage phase - long, short and irregular bones)
how many stages are there for intramembranous ossification and what are they
3
1) mesenchymal cells secrete osteoid and later defrentiate into osteoblasts (which produce new bone) and the decomposition of calcium salts lead to calcification.
2) blood vessels grow into area to supply oxygen and nutrients
3) initially cancellous bone but later compact bone develops
how many stages are there for endochondral ossification and what are they
6
1) small areas of osteogenic cells (cartilage model laid down)
2) osteoblasts produce bone collar and blood supply develops
3) cells in diaphysis (shaft of long bone) differentiate into blastocysts - primary ossification centres
4) osteoclasts erode centre of diaphysis to create bone marrow cavity
5) secondary ossification centres develop in the epiphyses (the expanded articular end of a long bone) and epiphyses cartilage is replaced by bone
6) thin plates of cartilage remain at the metaphysis
what continues to be laid down during bone growth
new cartalidge at the epiphyseal side of epiphyseal plate (end of bones). As epiphysel plate narrows bone growth is reduced
for how long will the bone continue to grow
for as long as the rate of cartilage growth exceeds the rate of osteoblast activity as its the osteoblasts that replace the cartilage with bone
what 3 hormones increase bone growth at puberty
sex, growth and thyroid hormones