Signaling Pathways of Hormones Flashcards
FSH
cAMP
Prolactin
Nonreceptor tyrosine kinase (JAK/STAT pathway)
Aldosterone
Intracellular receptor
Thrombopoietin
Nonreceptor tyrosine kinase (JAK/STAT pathway)
ADH (V1)
IP3
Progesterone
Intracellular receptor
GH
Nonreceptor tyrosine kinase (JAK/STAT pathway)
B1
cAMP
M3
IP3
Histamine (H2)
cAMP
Insulin
Receptor tyrosine kinase (MAP Kinase pathway)
A1
IP3
M1
IP3
Erythropoietin
Nonreceptor tyrosine kinase (JAK/STAT pathway)
EDRF (NO)
cGMP
Glucagon
cAMP
CRH
cAMP
Pneumonic for cGMP
BAD GraMPa
BNP, ANP, EDRF (NO)
(think vasodilators)
TRH
IP3
B2
cAMP
PPAR
Intracellular receptor
Pneumonic for Receptor Tyrosine Kinase
This is a MAP Kinase pathway
Think Growth Factors
Insulin, IGF-1, FGF, PDGF, EGF
FGF
Receptor tyrosine kinase (MAP Kinase pathway)
Pneumonic for Intracellular receptor
PET CAT on TV
Progesterone, Estrogen, Testosterone, Cortisol, Aldosterone, T3/T4, Vitamin D
Estrogen
Intracellular receptor
MSH
cAMP
EGF
Receptor tyrosine kinase (MAP Kinase pathway)
TSH
cAMP
Histamine (H1)
IP3
ACTH
cAMP
Vitamin D
Intracellular receptor
Testosterone
Intracellular receptor
ADH (V2)
cAMP
hCG
cAMP
Cortisol
Intracellular receptor
T4
Intracellular receptor
Vitamin A
Intracellular receptor
GHRH
cAMP
PTH
cAMP
Fatty acids
Intracellular receptor
Oxytocin
IP3
Pneumonic for Nonreceptor tyrosine kinase
PIGG (L) ET (this is a JAK/STAT pathway)
Think acidophils and cytokines
Prolactin, Immunomodulators (eg cytokines) GH, G-CSF, EPO, Thrombopoietin
Antigen specific receptor on B and T Cells
Nonreceptor tyrosine kinase (JAK/STAT)pathway
Prostacyclin
cAMP
Immunomodulators/Cytokines
Nonreceptor tyrosine kinase (JAK/STAT pathway)
G-CSF
Nonreceptor tyrosine kinase (JAK/STAT pathway)
ANP
cGMP
PDGF
Receptor tyrosine kinase (MAP Kinase pathway)
BNP
cGMP
Pneumonic for cAMP
FLAT CHAMP
FSH, LH, ACTH, TSH, CRH, hCG, ADH (v2), MSH, PTH
Calcitonin, GHRH, Glucagon, Histamine (h2)
T3
Intracellular receptor
D1
cAMP
Pneumonic for IP3
GOAT HAG: “I pee 3 times every hour”
GnRH, Oxytocin, ADH(V1), TRH, Histamine (H1), Angiotensin II, Gastrin
(V1 and H1: the I in IP3 looks like a 1)
IGF-1
Receptor tyrosine kinase (MAP Kinase pathway)
Gastrin
IP3
Retinoid
Intracellular receptor
Angiotensin II
IP3
GnRH
IP3
LH
cAMP
Calcitonin
cAMP