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--Step Shit-- > Autoantibodies and Associated Disorders > Flashcards

Autoantibodies and Associated Disorders Flashcards

1
Q

Anti-SSA (Anti-Ro)

A

Sjogren Syndrome

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2
Q

Anti-CCP

A

Rheumatoid Arthritis (more specific)

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3
Q

lupus anticoagulant

A

SLE, antiphospholipid syndrome

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4
Q

Antithryoglobulin

A

Hashimoto thyroiditis

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5
Q

Anti-smooth muscle

A

Autoimmune Hepatitis Type 1

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6
Q

Anti Helicase (anti-Mi-2)

A

Polymyositis, dermatomyositis

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7
Q

Anti-glutamic acid decarboxylase

A

Type 1 diabetes mellitus

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8
Q

Anti-hemidesmosome

A

Bullous pemphigoid

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9
Q

Antiparietal cell

A

Pernicious anemia

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10
Q

Anticentromere

A

Limited scleroderma (CREST syndrome)

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11
Q

Anti-intrinsic factor

A

Pernicious anemeia

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12
Q

Anti-dsDNA

A

SLE

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13
Q

Anti-presynaptic voltage gated calcium channel

A

Labert-Eaton myasthenic syndrome

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14
Q

IgA anti-tissue transglutaminase

A

Celiac Disease

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15
Q

Anti-thyroid peroxidase

A

Hashimoto thyroiditis

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16
Q

Anti-U1 RNP (ribonucleoprotein)

A

Mixed Connective Tissue Disease

17
Q

Anti-Scl-70 (anti-DNA topoisomerase 1)

A

Diffuse Scleroderma

18
Q

Anti-SRP

A

Polymyositis, dermatomyositis

19
Q

Anitmitochondrial

A

Primary biliary cirrhosis

20
Q

Antiphospholipase A2 receptor

A

Primary membranous nephropathy

21
Q

Rheumatoid factor (IgM antibody against IgG Fc region)

A

Rheumatoid Arthritis

22
Q

Anticardiolipin

A

SLE, antiphospholipid syndrome

23
Q

Anti-Smith

A

SLE

24
Q

IgA anti-endomysial

A

Celiac Disease

25
Q

Antinuclear (ANA)

A

Nonspecific screening antibody often associated with SLE (and also seen in drug induced lupus)

26
Q

MPO-ANCA/p-ANCA

A

Microscopic polyangiitis
Eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome)
Ulcerative colitis

27
Q

Anti-SSB (Anti-La)

A

Sjogren Syndrome

28
Q

Anti-β2 glycoprotein

A

Antiphospholipid syndrome

29
Q

Antimicrosomal

A

Hashimoto thyroiditis

30
Q

Antisynthetase (eg. anti-Jo-1 or anti-histidyl-tRNA synthetase)

A

Polymyositis, dermatomyositis

31
Q

Islet cell cytoplasmic antibodies

A

Type 1 diabetes mellitus

32
Q

Anti-TSH receptor

A

Graves Disease

33
Q

Anti-ACh receptor

A

Myasthenia gravis

34
Q

PR3-ANCA/c-ANCA

A

Granulomatosis with polyangiitis (Wegener)

35
Q

Anti-desmoglein (1 and 3) (anti-desmosome)

A

Pemphigus vulgaris

36
Q

Anti-Histone

A

Drug Induced Lupus

37
Q

Anti-glomerular basement membrane

A

Goodpasture syndrome

--Step Shit-- (32 decks)

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