Serine/Threonine Kinases Flashcards
1
Q
Phosphorylation is a nucleophilic attack of the _____ group of the ________ onto the ________ molecule.
A
Hydroxyl; serine/threonine/tyrosine; ATP
2
Q
There are many more types of _____ than ______, indicating a wider range of ______.
A
Kinases; phosphatases; phosphatases.
3
Q
The ______ state of the glycine loop allows for exchange of ADP and ATP.
A
Opened
4
Q
The ______ state of the glycine loop positions the gamma phosphate for transferring.
A
Closed
5
Q
NF-ATc is kept in the cytoplasm by its ______ group.
A
Phosphate
6
Q
NF-ATc is dephosphorylated (activated) by ________.
A
Calcium-bound calcineurin
7
Q
Calcineurin is a ______.
A
Phosphatase