Genetic Imprinting Flashcards
1
Q
Less than ___ percent of the human genome is imprinted.
A
10
2
Q
Prader-Willi syndrome is characterized by hypereating, ____, ____, and ____.
A
short stature; hypogonadism; intellectual disability
3
Q
Between Prader-Willi syndrome and Angelman syndrome, severe intellectual disability is more common in ____.
A
Angelman syndrome
4
Q
____ and ____ are hallmarks of Angleman syndrome.
A
Spasticity; seizures
5
Q
Deletions usually occur in ____ and ____.
A
Prader-Willi syndrome; Angleman syndrome
6
Q
Activation or inactivation tends to result from methylation of _______.
A
CpG islands in gene-promoter regions
7
Q
Heritable modification must be ______.
A
established during gametogenesis, maintained after fertilization, and reversible.
