Sedative Hypnotic Drugs (M2) Flashcards

1
Q

What are the main actions of sedative-hypnotic drugs?

A
  1. sedation
  2. relief of anxiety (anxiolytic)
  3. Sleep (hypnosis)
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2
Q

What is the term for the “relief of anxiety”?

A

anxiolytic

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3
Q

What are equivalent barbiturates that are rarely used?

A
  1. glutethimide

2. meprobamate

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4
Q

What are the over the counter antihistaminic sleep aids?

A
  1. diphenhydramine

2. doxylamine

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5
Q

What is there a loss of that leads to narcolepsy?

A

orexin peptides in hypothalamic neurons

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6
Q

When should sedative-hypnotic drugs not be used?

A

with inhibitors of P450 and liver dysfunction

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7
Q

What kind of sleep pattern increases with hypnotic drugs?

A

NREM sleep (not as good as REM)

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8
Q

What are the lipid soluble barbiturates that penetrate the brain and cause anesthesia?

A
  1. Thiopental

2. Methohexital

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9
Q

Which of the sedative-hypnotic drug groups has a minimal tolerance?

A

Z-drugs

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10
Q

What are the three types of anxiety?

A
  1. secondary to systemic disease
  2. situational anxiety
  3. pyschological
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11
Q

What are the types antidepressants used to treat anxiety states?

A
  1. Selective serotonin reuptake inhibitors (SSRIs)

2. Serotonin-norepinephrine reuptake inhibitors (SNRIs)

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12
Q

What do you not take anxiety medications with?

A

other anti-anxiety meds (no combos)

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13
Q

What age group is more sensitive to sedative-hypnotic drugs?

A

elderly

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14
Q

On the scale from A-D and X, which letter corresponds to positive evidence of human fetal risk with the use of a medication?

A

D and X

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