Introduction (M1)

Question 1

What is the biomedical science concerned with the interaction of chemical substances with living cells, tissues, and organisms, especially by binding to regulatory molecules and activating or inhibiting normal body processes called?

Answer 1

Pharmacology

Question 2

What deals with the processes that determine the concentration of drugs in body fluids and tissues over time, including drug absorption, distribution, biotransformation (metabolism) and excretion called?

Answer 2

Pharmacokinetics

Question 3

What is the study if the actions of drugs on target organisms and is concerned with the mechanisms of the drug action?

Answer 3

Pharmacodynamics

Question 4

What is any substance that brings about a chemical change in biologic function through chemical actions?

Answer 4

a drug

Question 5

What is the thing that contains other substances besides the active drug to make them more convenient to use?

Answer 5

Medicines

Question 6

What is a drug with harmful effects and can kill called?

Answer 6

poisons

Question 7

What is a drug that can kill and is produced by a living organism called?

Answer 7

toxin

Question 8

What is the study of genetic influences on responses to drugs?

Answer 8

Pharmacogenetics

Question 9

What is the use of genetic info to guide choice of drug therapy on an individual basis called?

Answer 9

Pharmacogenomics

Question 10

What is the study of drug effects at the population level?

Answer 10

Pharmacoepidemiology

Question 11

What is the branch of pharm that deals with the undesirable effects of chemicals on living systems?

Answer 11

toxicology

Question 12

What is the medical science concerned with the use of drugs in the treatment of disease?

Answer 12

Pharmacotherapeutics

Question 13

What is the major problem with crude drug prep?

Answer 13

Difficult to quantify

Question 14

Where is the drug absorbed in alimentary or enteral routes of administration? 1. What are examples of this route? 2

Answer 14

1. GI tract

2. oral, rectal, sublingual

Question 15

What are the advantages of alimentary or enteral routes of administration?

Answer 15

1. safest
2. delivery is slow
3. high blood levels avoided
4. convenient
5. Does not require sterile

Question 16

What are the disadvantages of alimentary or enteral routes of administration?

Answer 16

1. Rate of absorption variable
2. irritation of mucosal surfaces
3. compliance not ensured
4. Hepatic metabolism may occur

Question 17

What is hepatic metabolism impacting the drug amount called? 1. How can this be avoided while still being enteral? 2

Answer 17

1. “First-pass effect”

2. sublingual route

Question 18

What are examples of parenteral routes of administration?

Answer 18

1. Intravenous (IV)
2. Intramuscular (IM)
3. subcutaneous (SC)
4. intraperitoneal (IP)
5. intra-arterial (IA)
6. intrathecal (IT)
7. transdermal
8. epidural
9. intraarticular

Question 19

What are the advantages of parenteral routes of administration?

Answer 19

1. rapid response
2. dose more accurate
3. alternative when other not possible

Question 20

What are the disadvantages of parenteral routes of administration?

Answer 20

1. increased side effects
2. sterile formulation and aseptic technique needed
3. local irritation

Question 21

How is the IM route of drug administration describe in terms of absorption rate

Answer 21

used to administer drug suspensions that are slowly absorbed

Question 22

Which drug formulation would be best for a patient that has trouble remembering to take their meds three times a day?

Answer 22

extended release

Question 23

What drug name do patients know from ads?

Answer 23

trade name

Question 24

What is the disadvantage of smaller drugs?

Answer 24

cannot be unique in shape, charge, and properties to bind to specific receptors

Question 25

What is the disadvantage of larger drugs?

Answer 25

do not diffuse readily btw compartments of the body