Salt and water balance Flashcards
does water follow sodium or does sodium follow water?
WATER follows SODIUM everywhere
what type of activity controls sodium levels?
mineralocorticoid activity
what is the main steroid involved in mineralacocorticoid activity?
aldosterone
too much mineralocorticoid activity=?
sodium retention
too little mineralocorticoid activity=?
sodium loss
if there is sodium loss there is also what?
water loss
what hormone controls water balance
ADH
how does ADH work?
acts on renal tubules to cause water reabsorption
which part of pituitary does ADH come from?
posterior
increased ADH does what to urine?
makes it more concentrated because less water in urine
decreased ADH does what to urine?
make it more dilute because more water in urine
what 2 things can cause decreased sodium concentration?
too much water
too little sodium
what 2 things can cause increase in sodium concentration?
too little water
too much sodium
malaise tiredness weight loss decreased appetite looks TANNED craves salty food low BP which falls more upon standing
ADDISONS!!!
what are the 2 stimuli for ADH release?
osmotic - in health
non osmotic- in disease- pain, vomiting, hyoptension
what us SIAD syndrome
syndrome of inappropriate antidiuresis
what is the basic problem causing too little water in diabetes insipidus?
disruption of pituitary /pit stalk so ADH cant be secreted so no water reabsorption and lots of water lost in urine
what are the 3 volume statuses?
hypovolaemic
euvolaemic
hypervolaemic
hypovolaemia in hyponatraemia
too little sodium
how is hypervolaemia often seen?
oedema
if you suspect adrenal failure what should you measure?
cortisol and ACTH
if too little sodium what do you do?
give sodium
of too much water what do you do?
fluid restriction
if too little water what do you do?
get rid of excess