Diabetes Flashcards
when did insulin first arrive?
23rd january 1922
what cells attack the islets in type 1 diabetes?
lymphocytes
what are the typical presenting symptoms of type 1 diabetes?
polyuria
polydipsia
weight loss
fatugue
blurred vision
candidal infection
increased appetite
what test do you do to distinguish between types of diabtetes?
antibody test
how are newly diagnosed patients managed?
blood glucose and ketone monitoring insulin carb estimation regular DSN and dietician contact appropriate medical clinic review
annual review assessment
regular check of prevailing glycaemic control, HbA1c range
record severe hypoglycaemic episodes
what is late onset diabetes of adult hood?
elevated levels of pancreatic antibodies in patients with recently diagnosed diabetes who dont initially need insulin
what are the other names for late onset diabetes of adult hood?
slowly progressive type 1
type 1.5
when should you suspect late onset diabetes of adult hood?
25-40 yrs male (more likely) usually not obsese auto antibody positive associated with auto immune conditions
non insulin requiring at diagnosis
sub optimal control on oral agents
is diabetes common in cystic fibrosis?
yes
diabetes insipidus diabetes mellulitis optic atrophy deafness neurological abnormalities
wolfram syndrome (DIDMOAD)
often very obese polydactyly hypogonadal visual impairment hearing impairment mental retardation diabetes
consaguineous parents
Bardet-Biedl Syndrome
name some associated auto immune conditions for diabtetes?
coeliac thyroid disease pernicious anaemia addisons IgA deficiency