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Endocrine > Pathology of Pituitary and Adrenal gland > Flashcards

Pathology of Pituitary and Adrenal gland Flashcards

1
Q

name the trophic hormones secreted from anterior pituitray?

A

TSH
ACTH
FSH
LH

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2
Q

what are the non trophic hormones secreted from the anterior pituitary?

A

GH

Prolactin

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3
Q

what is derived from rathke’s pouch?

A

anterior pituitary

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4
Q

name the most common functional pituitary adenoma?

A

prolactinoma

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5
Q

name functional pituitary adenomas?

A

prolactinoma

GH secreting
ACTH secreting

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6
Q

what can cause pituitary hypofunction?

A 
tumours
trauma
surgery/radiation
granulomatous inflammation
infection
haemorrhage
hypothalmic lesions
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7
Q

what is craniopharyngioma?

A

derived from remnants of rathke’s pouch
slow growing, cystic, may calcify

headaches, visual disturbance

excellent prognosis

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8
Q

what can cause diabetes insipidus?

A

ADH insufficiency

renal resistance to ADH

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9
Q

what are the 3 zones of adrenal cortex?

A

zona glomerulosa

zona fascicultata

zona reticularis

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10
Q

what hormones come from the zona glomerulosa?

A

mineralacocorticoids

aldosterone

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11
Q

what hormones come from zona fasciculata?

A

glucocorticoids

cortisol

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12
Q

what hormones come from zona reticularis?

A

sex steroids

glucocorticoids

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13
Q

what do chromaffin cells in teh adrenal medulla scerete?

A

catecholamines

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14
Q

what can cause hyperfunction of the adrenals?

A

hyperplasia
adenoma
carcinoma

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15
Q

what can cause acute and chronic hypofunction of adrenals?

A

acute-waterhouse friderichsen

chronic- addisions

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16
Q

describe an adrenocortical adenoma?

A

well circumscribed, encapsulated lesion, usually small

yellow/brown cut surface (lipids)

well differentiated, small nuclei

17
Q

features suggesting adrenocrotical carcinoma?

A 
lareg size
haemorrhage and necrosis
frequent mitoses
lack of clear cells
capsular or vascular invasion
18
Q

what is primary hyperaldosteronism also known as?

A

conn’s syndrome

19
Q

too much cortisol

A

cushings

20
Q

3 common causes of addisons disease?

A

autoimmune
infection
metastatic malignancy

21
Q 
weakness, fatigue
anorexia/weight loss
nausea
diarrhoea
tanned!
pigmentation
A

addisons

22
Q

what are the 2 main adrenal medullary tumours?

A

neuroblastoma

phaechromocytoma (10% tumour)

23
Q

what tumour is also known at the 10% tumour?

A

phaechromocytoma

24
Q

catecholamines in urine?

A

phaechromocytoma

25
Q

medullary tumour assocaited with multiple endocrine neoplasia?

A

phaechromocytoma

Endocrine (29 decks)

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