Hormones and Receptors Flashcards

1
Q

who do endocrine glands communicate?

A

by hormone secretion

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2
Q

do endocrine glands have ducts?

A

no

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3
Q

name some overfall functions of the endocrine system

A

regulation of nutrient metabolsim, H2O and elctrolyte balance
enabling changes to stress
promote growth and development
control reproduction
controlling and integrating activities of cardio and digestive enzymes

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4
Q

what are the 3 main classes of hormones?

A

glycoproteins and peptides (insulin)

steroids e.g testosterone

tyrosine and tryptophan derivatives e.g adrenaline

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5
Q

how are amines transported in plasma?

A

mainly free as hydrophilic

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6
Q

how are peptides and proteins transported in plasma?

A

mainly free as hydrophilic

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7
Q

how are steroids transported in the plasma?

A

bound as hydrophobic

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8
Q

are steroids stored anywhere?

A

no

they are made and released on demand

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9
Q

what is the job of carrier proteins?

A

so carry steroids and thyroxine

they increase the amount transported in blood and prevent rapid excretion by preventing filtration by kidneys

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10
Q

what carrier protein binds to cortisol?

A

cortisol-binding globulin

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11
Q

what carrier protein binds to thyroxine?

A

thyroxine binding globulin

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12
Q

how do steroid hormones enter cells/

A

by diffusion

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13
Q

what does the sex steroid-binding globulin mainly bind to?

A

testosterone

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14
Q

what does albumin bind?

A

steroids and thyroxine

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15
Q

what does transthyretin bind?

A

thyroxine and some steroids

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16
Q

what are the main 3 types of hormone receptors?

A

G -protein coupled receptors
receptor kinases
nuclear receptor

17
Q

which receptors are on the cell surface?

A

G protein coupled receptors and receptor kinases

18
Q

what are the 3 classes of nuclear receptors?

A
class 1
class 2
hybrid
19
Q

what activates the class 1 nuclear receptors?

A

mainly steroids

20
Q

what activates the class 2 nuclear receptors?

A

mainly lipids

21
Q

what activated the hybrid class nuclear receptors?

A

thyroid hormone