Hormones and Receptors Flashcards
who do endocrine glands communicate?
by hormone secretion
do endocrine glands have ducts?
no
name some overfall functions of the endocrine system
regulation of nutrient metabolsim, H2O and elctrolyte balance
enabling changes to stress
promote growth and development
control reproduction
controlling and integrating activities of cardio and digestive enzymes
what are the 3 main classes of hormones?
glycoproteins and peptides (insulin)
steroids e.g testosterone
tyrosine and tryptophan derivatives e.g adrenaline
how are amines transported in plasma?
mainly free as hydrophilic
how are peptides and proteins transported in plasma?
mainly free as hydrophilic
how are steroids transported in the plasma?
bound as hydrophobic
are steroids stored anywhere?
no
they are made and released on demand
what is the job of carrier proteins?
so carry steroids and thyroxine
they increase the amount transported in blood and prevent rapid excretion by preventing filtration by kidneys
what carrier protein binds to cortisol?
cortisol-binding globulin
what carrier protein binds to thyroxine?
thyroxine binding globulin
how do steroid hormones enter cells/
by diffusion
what does the sex steroid-binding globulin mainly bind to?
testosterone
what does albumin bind?
steroids and thyroxine
what does transthyretin bind?
thyroxine and some steroids