hyper/hypo thyroidism Flashcards
TSH low
T3/4high
hyperthyroidism
TSH high
T3/4
hypothyroidism
TSH low
T3/4 low
pituitary gland failure
TSH high
T3/4 high
TSH oma
very rare!!!
TSH high, low T4
low or normal T3
primary overt hypo
high TSH norm T4 norm T3
primary subclinical hypo
low or normal TSH
low T4
low or normal T3
secondary hypo
what causes goitrous hypothyroidism?
chronic thyroiditis (hashimotos)
iodine deficiency
what causes non goitrous hypothyroidism?
congenital development defect
atrophic thyroiditis
post ablative
post radiation
characterised by thyroid peroxidase antibodies and T cell infiltrate and inflammation
Hashimotos
signs and symptoms of hypothyroidism?
coarse sparse hair dull expressionless face pale, dull skin that feels doughy vitilgo cold intolerance pitting oedema reduced heart rate decreased appetite weight gain constipation deep hoarse voice ascites obstructive sleep apnoea depression slow relfexes muscle stiffness/ cramps carpal tunnel syndrome
increased LDL
increased creatinine kinase
hypothyroidism
management of hypothyroidism
thyroxine (best before breakfast)
what does amiodarone induce?
hypothyroidism and thyrotoxicosis
hyperthyroidism signs and symptoms?
palpitations/AF tremor sweating anxiety sleep disturbance diarrhoea lid retraction eyes bulge out rapid finger nail growth brittle thinning hair less periods /lighter bleeding muscle weakness weight loss increased appetite