endocrinolgy and pregancy Flashcards
what hormone does the corpus luteum secrete?
progesterone
what hormones does the placenta secrete?
human placental lactogen
placental progesterone
placental osetrogen
what do progesterones and hPl cause in a mother?
insulin resistance
name some thing which could happen to a baby of a diabetic mother?
spina bifida caudal regression syndrome ureteric duplication resp distress syndrome hypoglycaaemia hypocalcaemia
when does the foetus produce its own insulin?
3rd trimester
what supplements should a diabetic mother take?
folic acid
what should a mother take for hypertension with pregnant?
labetalol
or nifedipine
methyldopa
how do prevent diabetes after GDM?
keep weight as low as possible healthy diet aerobic exercise metaformin? annual fasting glucose
in pregnancy what happens regarding the thyroid?
there is increased demand on the thyroid so it increases in size and produces more T4 just to maintain normal concentrations
plasma protein binding increases during pregnancy.. true or false?
true
how do you treat hypothyroidism in pregnancy?
increase thyroxine dose by 25mcg as soon as pregnancy is suspected
how do you treat hyperthyroidism in pregnancy?
wait and see
B blockers if need be
LOW DOSE antithyroid drugs-carbimazole 2nd and 3rd trimester
propylthiouracil 1st trimester
when should carbimazole be given in pregnancy?
2nd /3rd trimester
when should propylthiouracil be given in pregnancy?
1st trimester
why do you need to check for TRAb antibodies during pregnancy?
because if present they can cross the placenta and cause neonatal transient hyperthyroidism
