salivary secretion Flashcards

1
Q

What are the constituents of saliva?

A
  • water
  • electrolytes
  • organic components
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2
Q

mechanisms & control of salivary secretion

A
  • Initial acinar secretion of H2O and electrolytes
  • ductal modification of primary saliva
  • secretion of organic components
  • control of secretory mechanisms
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3
Q

describe primary acinar secretion

A
  • Ionic concentrations similar to plasma
  • Concentrations unaffected by flow rate
  • Will undergo modification in the ductal system
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4
Q

Describe ductal modification

A
  • little change in intercalated ducts
  • large change in composition in the striated ducts:
  • conversion from isotonic to a hypotonic solution
  • resorption of Na+ and Cl-
  • secretion of HCO3- and K+
  • dependant upon flow rate
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5
Q

describe the effect of flow rate (low flow rates)

A
  • much time for resorption of Na+
  • result very low (Na+) in saliva
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6
Q

describe the effect of flow rate (high flow rates)

A
  • less time for resorption of Na+
  • result less reduction (Na+) in saliva
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7
Q

effect of flow rate

A

high gland activity
- increased HCO3- bicarbonate in saliva

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8
Q

formation of organic components

A

synthesis of protein in association with ribosomes on the RER requires ATP from mitochondria

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9
Q

describe autonomic nervous system

A

the sympathetic and parasympathetic divisions of the ANS often work in a opposing fashion to maintain homeostasis

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10
Q

describe parasympathetic

A

coordinates the body’s basic homeostatic functions

  • conserves energy and maintains basal homeostasis
  • pre-ganglionic neurons from brainstem and S2-S4
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11
Q

describe sympathetic

A

coordinates the body’s response to stress, associated with fight, flight and fright reactions

  • pre-ganglionic neurons from T1-L2
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12
Q

What is a ganglion?

A

collection of nerve cell bodies in the periphery

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13
Q

describe one of the neuron peripheral chain

A

Pre-ganglionic neuron
- originates in brain or spinal cord
- synapse in a Ganglion

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14
Q

describe another of the neuron peripheral chain

A

Post-ganglionic neuron
- originates in the ganglion
- terminates in the effector organ/tissue

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15
Q

sympathetic control of salivary secretion

A

target transmitter: noradrenaline
- does not inhibit salivary secretion
- increased exocytosis of organic components
- contraction of myoepithelial cells

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