saliva secretion mechanism Flashcards
for what proportion of saliva secretion do the minor glands account for
10%
how many ducts does the sublingual gland have
10-20
what is wartons duct
the submandibular duct
where is the superior salivatory nucleus found
in the pons of the brain
which cranial nerves supply the submandibular and sublingual gland
the facial and trigeminal
which cranial nerve supplies the parotid gland
glossopharyngeal
which receptors found in the saliva activate secretion
chemoreceptors and mechanoreceptors
which kind of saliva is likely to be produced from sympathetic innervation
viscous, protein rich saliva
describe the mechanism of primary saliva secretion
- blood flow to the glands will determine the volume of aliva
- potassium, sodium, chloride and bicarbonate ions enter the acinus of the salivary gland
- water enters the acinus through aquaporins
- this is primary saliva and will enter the duct for modification from the ductal cells
which stimulator is produced from the parasympathetic nervous system
acetylcholine
which stimulator is produced from the sympathetic nervous system
noradrenaline
how does sodium enter the acinus
paracellular transport
how does chloride get into the acinus
CFTR proteins and sodium potassium pumps
how does bicarbonate enter the acinus
cells produce carbon dioxide which combines with water and carbonic anhydrase to produce carbonic acid
carbonic acid broken down into protons and bicarbonate.
bicarbonate excreted into the acinus
what happens when saliva enters the ducts
sodium ions move out of the saliva into the ductal cells
chloride ions also move out due to bicarbonate entry
this makes the saliva go from isotonic to hypotonic
