SAD - Chapter 11 - Misc Alopecias

Question 1

What are the characteristic features of pattern alopecia/baldness?

Answer 1

noninflammatory, nonpruritic, slowly progressive alopecia, miniaturization of hairs in the affected areas

Question 2

Most common breeds affected by canine flank alopecia

Answer 2

Boxer, Airedale terrier, English bulldog, schnauzers

Question 3

Histopathologic features of canine flank alopecia

Answer 3

follicular atrophy, infundibular hyperkeratosis, base of follicles are atrophic and hair bulbs misshapen – “witches feet”; melanized sebaceous glands

Question 4

T/F: Canine flank alopecia is often associated with hypothyroidism.

Answer 4

False - not been associated with any other metabolic or internal problems

Question 5

With anagen effluvium, how quickly after the initial insult does hair loss occur? Why?

Answer 5

within days of the insult (antimitotic drug, infectious disease, endocrine or metabolic disease); disrupts the growth phase

Question 6

With telogen effluvium, how quickly after the initial insult does hair loss occur?

Answer 6

1-3 months; stressful circumstance causes abrupt premature cessation of growth of anagen hair follicles –> synchronization of these follicles in catagen –> telogen

Question 7

What is the most common chemotherapeutic drug to cause telogen effluvium?

Answer 7

doxorubicin

Question 8

What is the most common iniciting cause for telogen effluvium?

Answer 8

partrurition (post-partum teolgen effluvium)

Question 9

T/F: Biopsy is helpful in confirming a diagnosis of anagen or telogen effluvium.

Answer 9

False - in telogen effluvium, change has already occurred; in anagen effluvium, only the hair is affected and the abnormal hairs are often lost when hair is clipped for biopsy

Question 10

How long after a rabies vaccine do lesions of post-rabies panniculitis typically appear?

Answer 10

1-3 months

Question 11

T/F: Injections of repository glucocorticoids can result in focal areas of alopecia with or without an associated swelling.

Answer 11

TRUE

Question 12

A topical product containing metaflumizone and amitraz can induce what type of reaction?

Answer 12

localized or generalized pemphigus foliaceus-like lesions

Question 13

Erythema ab igne occurs as a result of what exposure?

Answer 13

prolonged and repetitive exposure to moderate heat

Question 14

What are the clinical lesions of erythema ab igne?

Answer 14

alopecia, erythema and hyperpigmentation surrounding an area of central hypopigmentation; scaling, crusting, or ulceration

Question 15

What are the characteristic histopathologic features of erythema ab igne?

Answer 15

eosinophilic wavy elastic fibrils in the superficial dermis; laminar fibrosis of the superficial dermis

Question 16

Feline pinnal alopecia has been reported in what breed?

Answer 16

Siamese cats

Question 17

Feline paraneoplastic alopecia is most commonly associated with what malignancies?

Answer 17

pancreatic or bile duct carcinomas

Question 18

What histopathologic changes differentiate feline paraneoplastic alopecia from hypercortisolism?

Answer 18

acanthosis and parakeratosis, lack of trichilemmal keratin

Question 19

What are the histopathologic features of thymoma-induced exfoliative dermatitis?

Answer 19

hydropic interface dermatitis with some apoptosis