rheumatology Flashcards
if patient allergic to aspirin what DMARD should be given with caution
sulfalasazine
what arthritis is caused by IBD
enteropathic
risk factor for pseudo gout
hyperparathyroidism
hypothyroidism
is CRP normal or elevated in systemic lupus erythematosus
normal
what antibiotic cannot be prescribed with methotrexate
trimethoprim
for acute attacks of gout what do you give
colchicine
investigation for ankylosing spondylitis
plain radiograph of pelvis
joint aspirate of rheumatoid arthritis
high WBC count
polymorphonuclear neutrophils
yellow and cloudy
positive cardiolipin antibody suggest
antiphospholipid syndrome
pencil in cup deformity on Xray is suggestive of
psoriatic arthritis
what is important to monitor in a patient taking hydroxychloroquine
visual acuity - result in severe, permanent retinopathy
low calcium and phosphate
raised ALP
with generalised bone pain and muscle weakness
osteomalacia
what is squaring of the thumb a characteristic feature of
osteoarthritis
What is the main side effect of bisphosphonates
oesophageal restrictions including oesophagitis, ulcers, erosions
What causes eye problems in GCA
anterior ischaemic optic neuropathy
What gene for behcets diseases
HLA-B51
Symptoms of Behçet’s disease
- anterior uveitis
- oral ulcer
- genital ulcers
Felty’s syndrome
rheumatoid arthritis
Splenomegaly
Neutropenia
Antiphospholipid syndrome in pregnancy
LMWH
1st line investigation for GCA
ECR
what does co-trimoxazole contain
trimethoprim
- do not prescribe with methotrexate
ankylosing spondylitis features
the A’s
- apical fibrosis
- anterior uveitis
- aortic regurgitation
- achilles tendonitis
- AV node block
- amyloidosis
children and adolescents, growing lump on posterior aspect of thigh that is painful
onion skin appearance on radiograph =
ewings sarcoma
what is febuxostat used for
gout
what is etanercept an example of
anti TNF
proximal muscle weakness + rash around eyelids (heliotrope rash) =
dermatomyositis
dermatological finding in Behcets disease
erythema nodosum
underlying condition in dermatomyositis
internal malignancy
is there muscle weakness in poly myalgia rheumatica
no
sunburst pattern on radiograph
osteosarcoma
what antibodies are associated with drug induced lupus
anti histone antibodies
best diagnostic test for granulomatosis with polyangitis
cANCA
what should be checked before starting azathioprine
thiopurine methyltransferase deficiency
what should be managed before giving bisphosphonates
calcium / vit D deficiency
what is sausage fingers also described as
dactylics
- seen in psoriatic arthritis
riddle for reactive arthritis
can’t see, can’t pee, can’t climb a tree
if getting chemotherapy what are you at increased risk of
gout
asymmetrical presentation of stiffness that is relieved by exercise is suggestive of
psoriatic arthritis rather than rheumatoid
initial investigation for systemic lupus erythematosus
ANA
