rheumatology Flashcards

1
Q

if patient allergic to aspirin what DMARD should be given with caution

A

sulfalasazine

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2
Q

what arthritis is caused by IBD

A

enteropathic

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3
Q

risk factor for pseudo gout

A

hyperparathyroidism
hypothyroidism

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4
Q

is CRP normal or elevated in systemic lupus erythematosus

A

normal

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5
Q

what antibiotic cannot be prescribed with methotrexate

A

trimethoprim

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6
Q

for acute attacks of gout what do you give

A

colchicine

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7
Q

investigation for ankylosing spondylitis

A

plain radiograph of pelvis

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8
Q

joint aspirate of rheumatoid arthritis

A

high WBC count
polymorphonuclear neutrophils
yellow and cloudy

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9
Q

positive cardiolipin antibody suggest

A

antiphospholipid syndrome

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10
Q

pencil in cup deformity on Xray is suggestive of

A

psoriatic arthritis

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11
Q

what is important to monitor in a patient taking hydroxychloroquine

A

visual acuity - result in severe, permanent retinopathy

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12
Q

low calcium and phosphate
raised ALP
with generalised bone pain and muscle weakness

A

osteomalacia

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13
Q

what is squaring of the thumb a characteristic feature of

A

osteoarthritis

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14
Q

What is the main side effect of bisphosphonates

A

oesophageal restrictions including oesophagitis, ulcers, erosions

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15
Q

What causes eye problems in GCA

A

anterior ischaemic optic neuropathy

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16
Q

What gene for behcets diseases

17
Q

Symptoms of Behçet’s disease

A
  • anterior uveitis
  • oral ulcer
  • genital ulcers
18
Q

Felty’s syndrome

A

rheumatoid arthritis
Splenomegaly
Neutropenia

19
Q

Antiphospholipid syndrome in pregnancy

20
Q

1st line investigation for GCA

21
Q

what does co-trimoxazole contain

A

trimethoprim
- do not prescribe with methotrexate

22
Q

ankylosing spondylitis features

A

the A’s
- apical fibrosis
- anterior uveitis
- aortic regurgitation
- achilles tendonitis
- AV node block
- amyloidosis

23
Q

children and adolescents, growing lump on posterior aspect of thigh that is painful
onion skin appearance on radiograph =

A

ewings sarcoma

24
Q

what is febuxostat used for

25
what is etanercept an example of
anti TNF
26
proximal muscle weakness + rash around eyelids (heliotrope rash) =
dermatomyositis
27
dermatological finding in Behcets disease
erythema nodosum
28
underlying condition in dermatomyositis
internal malignancy
29
is there muscle weakness in poly myalgia rheumatica
no
30
sunburst pattern on radiograph
osteosarcoma
31
what antibodies are associated with drug induced lupus
anti histone antibodies
32
best diagnostic test for granulomatosis with polyangitis
cANCA
33
what should be checked before starting azathioprine
thiopurine methyltransferase deficiency
34
what should be managed before giving bisphosphonates
calcium / vit D deficiency
35
what is sausage fingers also described as
dactylics - seen in psoriatic arthritis
36
riddle for reactive arthritis
can't see, can't pee, can't climb a tree
37
if getting chemotherapy what are you at increased risk of
gout
38
asymmetrical presentation of stiffness that is relieved by exercise is suggestive of
psoriatic arthritis rather than rheumatoid
39
initial investigation for systemic lupus erythematosus
ANA