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COMLEX 3 > Rheum > Flashcards

Rheum Flashcards

1
Q

how many WBC on arthrocentesis indicates septic joint?

A

> 50k

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2
Q

ANA Ab –> indicates what dz/condition?

A

sensitive lupus

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3
Q

histone Ab –> indicates what dz/condition?

A

specific drug-induced lupus

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4
Q

ds-DNA Ab –> indicates what dz/condition?

A

specific lupus + renal involvement

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5
Q

smooth muscle Ab –> indicates what dz/condition?

A

autoimmune hepatitis

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6
Q

mitochondrial Ab –> indicates what dz/condition?

A

primary biliary cirrhosis

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7
Q

centromere Ab –> indicates what dz/condition?

A

scleroderma (CREST)

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8
Q

RO + LA Ab –> indicates what dz/condition?

A

sjogren’s

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9
Q

CCP Ab –> indicates what dz/condition?

A

rheumatoid arthritis

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10
Q

RF Ab –> indicates what dz/condition?

A

rheumatoid arthritis

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11
Q

Jo Ab –> indicates what dz/condition?

A

polymyositis

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12
Q

topoisomerase (scl-70) Ab –> indicates what dz/condition?

A

systemic scleroderma

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13
Q

Marfan disease –> assoc with what heart conditions (2)?

A
  • mitral valve prolapse

- aortic aneurysm

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14
Q

Smith Ab –> indicates what dz/condition?

A

SLE

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15
Q

38F –> c/o painful vaginal ulcers & “watery eyes” w blurred vision –> h/o oral ulcers –> multiple episodes of same

Condition?

A

Behcet dz

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16
Q

Behcet dz –> presentation

A
  • genital ulcer
  • oral ulcer
  • uveitis
17
Q

Behcet dz –> acute flare –> tx

A

prednisone PO

18
Q

CREST synd –> presentation

A
  • Calcinosis
  • Raynaud phenomenon
  • Esophageal dysmotility
  • Sclerodactyly
  • Telangiectasia

commonly affect fingers and face

19
Q

differentiate: pauciartericular juvenile idiopathic arthritis vs polyarticular juvenile idiopathic arthritis

A

pauci:
- rheumatoid factor negative
- <5 joints
- large jts

poly:
- RF positive
- >4 jts
- any joints

20
Q

systemic scleroderma –> scleroderma renal crisis –> tx

A

ACEI

21
Q

gadolinium –> afterwards develops Cr increase, sclerodactyly, raynaud’s

what condition?

A

nephrogenic systemic sclerosis

22
Q

myositis (ie inclusion body myositis, polymyositis, dermatomyositis) –> pathognomonic exam finding (3)

A
  • heliotrope rash
  • grotton’s papule
  • shawl sign
23
Q

myositis (ie inclusion body myositis, polymyositis, dermatomyositis) –> presentation

A
  • subacute painless
  • proximal muscle weakness
  • derm findings
24
Q

myositis (ie inclusion body myositis, polymyositis, dermatomyositis) –> followup management

A

can be assoc w malignancy –> cancer screening approp for age

25
Q

proximal muscle weakness, skin changes –> suspect myositis –> next step in dx

A
  • CK: muscle problem?

- EMG: muscle or nerve problem?

COMLEX 3 (17 decks)

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