Rheum

Question 1

how many WBC on arthrocentesis indicates septic joint?

Answer 1

> 50k

Question 2

ANA Ab –> indicates what dz/condition?

Answer 2

sensitive lupus

Question 3

histone Ab –> indicates what dz/condition?

Answer 3

specific drug-induced lupus

Question 4

ds-DNA Ab –> indicates what dz/condition?

Answer 4

specific lupus + renal involvement

Question 5

smooth muscle Ab –> indicates what dz/condition?

Answer 5

autoimmune hepatitis

Question 6

mitochondrial Ab –> indicates what dz/condition?

Answer 6

primary biliary cirrhosis

Question 7

centromere Ab –> indicates what dz/condition?

Answer 7

scleroderma (CREST)

Question 8

RO + LA Ab –> indicates what dz/condition?

Answer 8

sjogren’s

Question 9

CCP Ab –> indicates what dz/condition?

Answer 9

rheumatoid arthritis

Question 10

RF Ab –> indicates what dz/condition?

Answer 10

rheumatoid arthritis

Question 11

Jo Ab –> indicates what dz/condition?

Answer 11

polymyositis

Question 12

topoisomerase (scl-70) Ab –> indicates what dz/condition?

Answer 12

systemic scleroderma

Question 13

Marfan disease –> assoc with what heart conditions (2)?

Answer 13

• mitral valve prolapse

- aortic aneurysm

Question 14

Smith Ab –> indicates what dz/condition?

Answer 14

SLE

Question 15

38F –> c/o painful vaginal ulcers & “watery eyes” w blurred vision –> h/o oral ulcers –> multiple episodes of same

Condition?

Answer 15

Behcet dz

Question 16

Behcet dz –> presentation

Answer 16

• genital ulcer
• oral ulcer
• uveitis

Question 17

Behcet dz –> acute flare –> tx

Answer 17

prednisone PO

Question 18

CREST synd –> presentation

Answer 18

• Calcinosis
• Raynaud phenomenon
• Esophageal dysmotility
• Sclerodactyly
• Telangiectasia

commonly affect fingers and face

Question 19

differentiate: pauciartericular juvenile idiopathic arthritis vs polyarticular juvenile idiopathic arthritis

Answer 19

pauci:
- rheumatoid factor negative
- <5 joints
- large jts

poly:
- RF positive
- >4 jts
- any joints

Question 20

systemic scleroderma –> scleroderma renal crisis –> tx

Answer 20

ACEI

Question 21

gadolinium –> afterwards develops Cr increase, sclerodactyly, raynaud’s

what condition?

Answer 21

nephrogenic systemic sclerosis

Question 22

myositis (ie inclusion body myositis, polymyositis, dermatomyositis) –> pathognomonic exam finding (3)

Answer 22

• heliotrope rash
• grotton’s papule
• shawl sign

Question 23

myositis (ie inclusion body myositis, polymyositis, dermatomyositis) –> presentation

Answer 23

• subacute painless
• proximal muscle weakness
• derm findings

Question 24

myositis (ie inclusion body myositis, polymyositis, dermatomyositis) –> followup management

Answer 24

can be assoc w malignancy –> cancer screening approp for age

Question 25

proximal muscle weakness, skin changes –> suspect myositis –> next step in dx

Answer 25

• CK: muscle problem?

- EMG: muscle or nerve problem?