OB/Gyn Flashcards
Which contraceptive has greatest risk of DVT/PE?
patch
pregnant –> positive for syphilis –> PCN allergy –> tx?
desensitize in ICU –> treat w PCN
DEXA scan –> at what age?
65yo
60yo if smoker
menopause –> what happens to FSH and anti-Mullerian hormone (increase/decrease)?
- increase FSH
- decrease AMH
how confirm rupture of membranes?
- vaginal pooling
- nitrazine test
- fern test
what is fetal fibronectin used for?
marker to assess likelihood of preterm labor bw 22-34wk pregnancy
fetal heart tone –> late decel –> indicates what?
uteroplacental insufficiency
fetal heart tone –> early decel –> indicates what?
fetal head compression –> increase vagal tone
fetal heart tone –> variable decel –> indicates what?
umbilical cord compression
pregnant –> DVT –> tx?
SQ LMWH
PID –> inpt tx –> abx?
- cefoxitin + doxy
- clinda + gent
PID –> outpt tx –> abx?
ceftriaxone + doxy + metro
secondary amenorrhea –> preg test negative –> next step?
check FSH, TSH, prolactin
Down synd –> quad screen results
- AFP decreased
- estriol decreased
- Bhcg increased
- inhibin increased
quad screen:
- AFP decreased
- estriol decreased
- Bhcg decreased
- inhibin decreased
what condition?
Trisomy 18
quad screen:
- AFP increased
- estriol normal
- Bhcg normal
- inhibin normal
what condition?
open neural tube defect
quad screen:
- AFP normal
- estriol normal
- Bhcg normal
- inhibin normal
what condition?
- normal fetus
- trisomy 13
quad screen:
- AFP normal
- estriol decreased
- Bhcg normal
- inhibin normal
what condition?
X-linked ichthyoses (steroid sulfatase deficiency)
chorionic villous sampling –> at what gestation can be performed?
9-11wk gestation
at what gestation can amniocentesis be performed?
15-20wk gestation
chorionic villous sampling prior to 9wk gestation increases fetal risk of what?
limb abnormalities
DEXA scan –> Tscore of what diagnoses osteoporosis?
< -2.5
DEXA scan –> Tscore of what diagnoses osteopenia?
-1 to -2.5
gestation diabetes –> when screen for it?
24-28wk gestation (2nd trimester)
pap –> atypical glandular cells –> next step
colposcopy w endocervical curettage
1st trimester –> genetic screen components
- UA nuchal translucency
- PAPP-A
- hCG
2nd trimester –> genetic screen components
triple screen:
- hCG
- AFP
- estriol
quad screen: inhibin-A
AFP –> elevated in what conditions (4)
- neural tube defect
- abdominal wall defect (gastroschisis, omphalocele)
- mult gestation
- error in gestational age
how dx gestational DM?
1hr gtt >140
```
then 3hr gtt:
- fasting >90
- 1hr >180
- 2hr >155
- 3hr >140
any 2
~~~
gestation DM –> tx
insulin (based on post-prandial sugars) <180
20-28wk gestation –> what conditions are screened for (3)
- gestational DM
- Rh Ag status
- maternal anemia
28wk gestation –> under what conditions give rhogam?
- mom is negative for Rh Ag and Rh Ab
- dad is Rh Ag+ or unknown
gestational DM –> goal fasting glucose
<95
3rd trimester –> painless vaginal bleeding –> what condition?
placenta previa
3rd trimester –> painful vaginal bleeding –> what condition?
placental abruption
placenta previa –> RF (3)
- prior C/S
- multiparity
- uterine surgery
3rd trimester –> vaginal bleeding –> next step
fetal ultrasound
placental previa –> pelvic exam is contraindicated –> T/F?
T
hydatidiform mole –> tx
D&C
hydatidiform mole –> tx w D&C –> followup management
monitior hCG –> continued high level can indicate malignancy (commonly mets to lung)
late decel –> uteroplacental insuff –> decreased oxygen delivery to fetus
MCC
excessive uterine contraction
late decel –> uteroplacental insuff – due to excessive uterine contraction
common cause of excessive uterine contraction
oxytocin administration
pap smear –> atypical cells of undetermined significance (ASCUS) –> next step
HPV screen
or repeat pap in 6-12mo
pap smear –> atypical cells of undetermined significance (ASCUS) –> HPV screen positive –> next step
colposcopy
pap smear –> stop at what age?
65yo
pap –> abnormal cells –> next step
colposcopy
abnormal pap –> colposcopy –> ecto positive, endo negative –> next step
local ablation:
- LEEP
- cryoablation
abnormal pap –> colposcopy –> ecto negative, endo positive –> next step
cone bx
HPV vaccine –> who?
F: 11-26
M: 11-21
pregnant –> BMI normal –> how much weight gain during pregnancy?
25-35 lb
pregnant –> BMI overweight –> how much weight gain during pregnancy?
15-25 lb
pregnant –> BMI underweight –> how much weight gain during pregnancy?
> 35 lb
pregnant –> BMI obese –> how much weight gain during pregnancy?
11-20 lb
pregnant –> how much daily folate supplementation?
400mcg
pregnant –> h/o son with spina bifida –> how much daily folate supplementation?
4000mcg
Asherman’s synd: labs
- FSH level: decreased/normal/increased?
- LH level: decreased/normal/increased?
normal ovarian fx
FSH: normal
LH: normal
uterine fundus –> at umbilicus
what gestational age?
20wk
17F pregnant –> 37wk gestation –> ER c/o vag bleed, intense pelvic pain –> VSS
dx? next step?
1 step: assess maternal & fetal status
placental abruption
mother is stable ==> next step is begin fetal monitor
next step is NOT pelvic exam, type&screen, or ABCs
nurse is pregnant –> cannot take care of patients with what infections (4)?
- parvovirus B19
- measles
- varicella
- rubella
dysfunctional uterine bleeding –> pathophys
unopposed production of estradiol –> anovulatory cycles
dysfunctional uterine bleeding –> acute bleeding –> acute tx for acute bleeding
high dose estrogen for 48hr
dysfunctional uterine bleeding –> acute bleeding trted w high dose estrogen –> return to ER after 3 days with continued profuse vaginal bleeding
next step? why?
D&C –> rule out endometrial CA
> 45F –> suspect anovulatory abnormal uterine bleed –> best initial diagnostic test
endometrial bx –> rule out cancer
endometrial bx shows endometrial CA –> check what tumor marker to evaluate for extrauterine spread?
CA-125
CA-125 –> extremely elevated –> indicates what condition?
ovarian CA
postmenopausal bleeding –> bx shows endometrial hyperplasia –> tx
progesterone
postmenopausal bleeding –> bx shows endometrial adenoCA –> tx
TAH+BSO
postmenopausal bleeding –> bx shows endometrial adenoCA –> mets –> chemotherapy regimen?
paclitaxel + doxorubicin + cisplatin
postmenopausal bleeding –> endometrial bx shows complex atypia
tx: progestin or surgery?
surgery
postmenopausal bleeding –> endometrial bx shows atypia
tx: progestin or surgery?
progestin
postmenopausal bleeding –> endometrial bx shows dysplasia
tx: progestin or surgery?
surgery
tamoxifen –> increases risk of what CA?
endometrial
pregnant –> vaginal bleeding
Passage of parts: no
Os: open
US: dead baby
dx?
inevitable abortion
pregnant –> vaginal bleeding
Passage of parts: yes
Os: open
US: retained parts
dx?
incomplete abortion
should be able to see fetus at what B-hCG level?
> 1500
vaginal bleeding –> UPT positive –> can’t see anything on TVUS –> B-hCG <1500
next step?
too early to see pregnancy on ultrasound –> repeat B-hCG quant in 48hr
vaginal bleeding –> UPT positive –> can’t see anything on TVUS –> B-hCG <1500 –> repeat in 48hr shows B-hCG has doubled
dx?
intrauterine pregnancy
vaginal bleeding –> UPT positive –> can’t see anything on TVUS –> B-hCG <1500 –> repeat in 48hr shows B-hCG has not doubled
dx?
ectopic pregnancy
Sheehan’s synd (postpartum hypopituitarism) –> presentation
- failure to lactate
- amenorrhea
- other hypopituitarism
Sheehan’s synd (postpartum hypopituitarism) –> when does it present?
days to years after delivery
prolactinemia –> tx
dopamine agonist:
- pramipexole
- ropinirole
prolactinoma –> tx
dopamine agonist:
- pramipexole
- ropinirole
NOT surgery
what is savage synd
resistant ovary synd –> ovaries resistant to gonadotropin –> ovarian failure –> 2ndary amenorrhea
blind ended vagina
what condition?
- androgen insensitivity synd (testicular feminization)
- mullerian agenesis
androgen insensitivity synd (testicular feminization) –> pathophys
46XY –> X-linked recessive dz –> external genitalia –> fail to masculinize
androgen insensitivity synd (testicular feminization) –> risk of what complication
intra-abdominal gonads –> risk of malignancy
primary amenorrhea –> FSH & LH are low
what condition?
- Kallman’s
- craniopharyngioma
primary amenorrhea + anosmia –> dx?
Kallman’s
Turner synd –> karyotype
XO
OCP can cause HTN
T/F?
T
what is raloxifene
SERM:
- breast cancer
- osteoporosis
raloxifene –> contraindication?
h/o DVT
hepatic adenoma –> assoc w what med?
- OCP
- anabolic steroid
pregnancy –> recommended daily increase in caloric intake
300 kcal/day
breast: 2ndary mound
what Tanner stage? what age?
age 13-15 –> Tanner 4
breast: enlarge
what Tanner stage? what age?
11.5-13yo –> Tanner 3
endometrial bx –> endometrial adenoCA –> next step is CT imaging
T/F
F
next step is TAH/BSO
late decels –> uteroplacental insuff –> tx?
- L lat decubitus
- O2
- d/c oxytocin
what is contraindication for administering Mg sulfate in eclampsia
myasthenia gravis
differentiate: compete vs partial molar pregnancy
complete:
- no fetus –> only moles
partial:
- fetus/amniotic fluid/gestational sac is present
PCOS –> tx for oligoovulation/amenorrhea?
clomiphene –> estrogen agonist/antagonist –> increase GnRH pulse amplitude –> increase LH/FSH –> ovulation
pubic: adult quality –> sparse distribution
what tanner stage?
Tanner stage 3
breast: breast bud
what tanner stage? what age?
10-11.5yo –> Tanner stage 2
ovarian cancer that cause SBO –> what kind?
mucinous epithelial carcinoma
what constitute severe preeclampsia?
- > 160/100
- 3+ proteinuria
- progressive renal fail