Neuro Flashcards
Meniere’s disease –> triad of ssx?
- vertigo
- hearing loss/fullness/tinnitus
- unrelated to movement
Meniere’s disease –> vertigo episodes –> duration?
~30min
BPPV –> vertigo episodes –> duration?
<1min
labyrinthitis/vestibular neuritis –> why is it a diagnosis of exclusion?
- pontine strokes/tumors also feature chronic vertigo
- recent URI often goes unnoticed
labyrinthitis/vestibular neuritis –> how long to resolve?
months
Meniere’s disease –> tx?
- thiazide diuretics
- low salt diet
- meclizine
central vertigo from posterior fossa lesion –> etiology ddx (6)?
- MS
- CVA
- tumor
- abscess
- migraine
- sz
pseudotumor cerebri –> occurs in who?
young obese F taking isotretinoin & OCPs
drug overdose –> hyperNa, met acidosis, hypoCa, elevated ammonia, mild elevated AST/ALT –> what drug?
valproic acid
what allele increases risk for Alzheimer’s?
apolipoprotein E4
Alzheimer’s –> volumetric MRI finding
- hippocampal asymmetry
- medial temporal lobe asymmetry
pseudotumor cerebri –> tx
- carbonic anhydrase inh (acetazolamide)
- systemic steroid
pseudotumor cerebri –> trt w acetazolamide –> goal of treatment
prevent blindness
L temporal AVM ruptures –> what condition?
subarachnoid hemorrhage
B12 deficiency –> presentation
- peripheral sensory neuropathy (stocking-glove)
- decreased DTR
- fatigue
B12 deficiency –> causes (3)
- pernicious anemia
- surgical resection of terminal ileum
- achlorhydria
34F –> hearing loss for 6mo –> Rinne test shows bone conduction is longer than air conduction –> mother also has hearing loss
what condition?
otosclerosis
Rinne test –> bone conduction is longer than air conduction –> what type of hearing loss?
conductive hearing loss
otosclerosis –> what reflex is abnormal?
loss of stapedial reflex
MCC of headache in children
migraine
cluster HA –> tx
O2
cluster HA –> 2nd line tx
triptan
cluster HA –> prophylaxis
verapamil
cluster HA –> workup
MRI head
pseudotumor cerebri (idiopathic intracranial HTN) –> dx
LP –> opening pressure >25
pseudotumor cerebri (idiopathic intracranial HTN) –> finding on imaging
normal
mercury poisoning –> tx
chelating agent:
- succimer
- penicillamine
- dimercaprol
exam shows fluid behind L ear –> Weber test shows louder vibration on left
dx?
L conductive hearing loss
conductive hearing loss –> Weber test result
affected ear –> detect sound longer
sensorineural hearing loss –> Weber test result
affected ear –> detect sound shorter
Rinne test –> tuning fork at mastoid –> switch to air –> patient does not hear
dx?
conductive hearing loss
status epilepticus –> mult doses of lorazepam –> but sz continues –> next step
phenytoin
status epilepticus –> mult doses of lorazepam –> phenytoin –> but sz continues –> next step
midazolam + propofol
generalized sz –> tx
- valproate (cheapest –> probably correct answer on exam)
- lamotrigine
- levetiracetam (less AE)
generalized sz vs myoclonic sz
generalized:
- whole body shaking
- LOC
myoclonic:
- no LOC
- increased muscle tone
myoclonic sz –> tx
valproate
atonic sz –> tx
valproate
pseudosz –> dx
24hr EEG w video monitoring –> induce sz w stimuli and sleep deprivation
status epilepticus –> dx
- sz >5min
- post-ictal state >20min
50M homeless –> h/o esophageal varices –> ER –> lethargy, absent lateral gaze, ataxia
condition?
Wernicke’s encephalopathy
Wernicke’s encephalopathy –> presentation (triad)
- confusion
- ophthalmoplegia
- ataxia
Wernicke’s encephalopathy –> cause
thiamine (B1) def
lumbar stenosis –> sit or lean forward –> pain worse or better?
pain is better
red flag ssx of cord compression –> next step
dexamethasone
give steroid BEFORE get imaging!
- painless progressive vision loss
- color desaturation
what condition?
vitB12 def
Guillain-Barre synd –> tx
- plasmapheresis
- IVIG
vertical nystagmus, myoclonus, 3+ reflexes bilaterally
what vit/electrolyte deficiency?
Mg def
Mg def –> presentation
muscular & neurologic hyperactivity
differentiate: cauda equina synd vs conus medullaris synd
cauda equina:
- unilat
- LMN signs only
conus medullaris:
- bilat
- UMN & LMN signs
cauda equina synd –> surgical decompression must be performed within how many hours of symptom onset?
48hr
CN III palsy –> persentation
- ptosis
- eye down & out
CN III palsy –> can be caused by aneurysm of what?
posterior communicating artery aneurysm
post-dural puncture HA (spinal HA) –> worsening despite conservative measures (bed rest, tylenol, caffeine, fluids) –> tx?
epidural blood patch –> inject venous blood into epidural space –> immediate relief
Guillain-Barre synd -> how dx?
- nerve conduction study
- LP
Guillain-Barre synd -> CSF results
- increased protein
- normal WBC